DegronMD - P47813(EIF1AX)

EIF1AX

UniProt ID: P47813

Entrez ID: 1964

Protein name: Eukaryotic translation initiation factor 1A, X-chromosomal (eIF-1A X isoform) (Eukaryotic translation initiation factor 4C) (eIF-4C)

External links: UniprotKB HGNC RefSeq COSMIC

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GO - Biological processes (BP): View more >>

GO - Molecular function (MF): View more >>

GO - Cellular component (CC): View more >>

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.R14W	TCGA-50-5049	LUAD	TCGA	RELVFKE	LIG_APCC_ABBAyCdc20_2	24:30	Mutation rewiring degron network	0.0556
p.R14W	DO23705	LUAD	ICGC	RELVFKE	LIG_APCC_ABBAyCdc20_2	24:30	Mutation rewiring degron network	0.0556
p.A36T	TCGA-D7-A4YV	STAD	TCGA	RELVFKE	LIG_APCC_ABBAyCdc20_2	24:30	Mutation rewiring degron network	0.1667
p.A36T	DO47777	STAD	ICGC	RELVFKE	LIG_APCC_ABBAyCdc20_2	24:30	Mutation rewiring degron network	0.1667
p.G15V	TCGA-DB-A4XB	LGG	TCGA	RELVFKE	LIG_APCC_ABBAyCdc20_2	24:30	Mutation rewiring degron network	0.0833
p.G15V	DO230344	COCA	ICGC	RELVFKE	LIG_APCC_ABBAyCdc20_2	24:30	Mutation rewiring degron network	0.0833
p.G15V	DO44546	LGG	ICGC	RELVFKE	LIG_APCC_ABBAyCdc20_2	24:30	Mutation rewiring degron network	0.0833
p.G15V	DO222753	MELA	ICGC	RELVFKE	LIG_APCC_ABBAyCdc20_2	24:30	Mutation rewiring degron network	0.0833
p.G15D	TCGA-DU-A5TP	LGG	TCGA	RELVFKE	LIG_APCC_ABBAyCdc20_2	24:30	Mutation rewiring degron network	0.0833
p.G15D	TCGA-V4-A9F7	UVM	TCGA	RELVFKE	LIG_APCC_ABBAyCdc20_2	24:30	Mutation rewiring degron network	0.0833
p.G15D	TCGA-WC-A87U	UVM	TCGA	RELVFKE	LIG_APCC_ABBAyCdc20_2	24:30	Mutation rewiring degron network	0.0833
p.G15D	DO44562	LGG	ICGC	RELVFKE	LIG_APCC_ABBAyCdc20_2	24:30	Mutation rewiring degron network	0.0833
p.R14G	SIDM00516	Melanoma	GDSC	RELVFKE	LIG_APCC_ABBAyCdc20_2	24:30	Mutation rewiring degron network	0.0556
p.R14G	ACH-002166	Skin Cancer	CCLE	RELVFKE	LIG_APCC_ABBAyCdc20_2	24:30	Mutation rewiring degron network	0.0556
p.R14G	MZ7-mel	skin	COSMIC	RELVFKE	LIG_APCC_ABBAyCdc20_2	24:30	Mutation rewiring degron network	0.0556
p.R34G	OPM-2	haematopoietic and lymphoid tissue	COSMIC	RELVFKE	LIG_APCC_ABBAyCdc20_2	24:30	Mutation rewiring degron network	0.2222
p.H32D	NCI-H196	lung	COSMIC	RELVFKE	LIG_APCC_ABBAyCdc20_2	24:30	Mutation rewiring degron network	0.2778

Kaplan plot for EIF1AX in

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*NOTE: the Kaplan plots were collected from OncoLnc