RGS19
UniProt ID: P49795
Entrez ID: 10287
Protein name: Regulator of G-protein signaling 19 (RGS19) (G-alpha-interacting protein) (GAIP)
External links: UniprotKB HGNC RefSeq COSMIC
Please click HERE
for better display.
FUNCTION: Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G-alpha subfamily 1 members, with the order G(i)a3 > G(i)a1 > G(o)a >> G(z)a/G(i)a2. Activity on G(z)-alpha is inhibited by phosphory...
FUNCTION: Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G-alpha subfamily 1 members, with the order G(i)a3 > G(i)a1 > G(o)a >> G(z)a/G(i)a2. Activity on G(z)-alpha is inhibited by phosphorylation and palmitoylation of the G-protein.
View more >>
GO - Biological processes (BP):
autophagy [GO:0006914]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of signal transduction [GO:0009968]; response to ethanol [GO:0045471]; small GTPase mediated signal transduction [GO:0007264]...
autophagy [GO:0006914]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of signal transduction [GO:0009968]; response to ethanol [GO:0045471]; small GTPase mediated signal transduction [GO:0007264]
View more >>
GO - Molecular function (MF):
G-protein alpha-subunit binding [GO:0001965]; GTPase activity [GO:0003924]...
G-protein alpha-subunit binding [GO:0001965]; GTPase activity [GO:0003924]
View more >>
GO - Cellular component (CC):
brush border [GO:0005903]; clathrin-coated vesicle [GO:0030136]; Golgi apparatus [GO:0005794]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]...
brush border [GO:0005903]; clathrin-coated vesicle [GO:0030136]; Golgi apparatus [GO:0005794]; membrane [GO:0016020]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]
View more >>
RGS19
Control panel
Show dataset:
Show Degron:
All sites
Degron
Degron
Filter mutation sites
All sites
Minimum 5 samples
Minimum 10 samples
Minimum 5 samples
Minimum 10 samples
Data table is loading....
Kaplan plot for RGS19 in
Download patient class data (Lower:Upper = 50%:50%)
*NOTE: the Kaplan plots were collected from OncoLnc