CAMP
UniProt ID: P49913
Entrez ID: 820
Protein name: Cathelicidin antimicrobial peptide (18 kDa cationic antimicrobial protein) (CAP-18) (hCAP-18) [Cleaved into: Antibacterial peptide FALL-39 (FALL-39 peptide antibiotic); Antibacterial peptide LL-37]
External links: UniprotKB HGNC RefSeq COSMIC
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FUNCTION: Binds to bacterial lipopolysaccharides (LPS) and has antibacterial activity (PubMed:16637646, PubMed:18818205). Acts via neutrophil N-formyl peptide receptors to enhance the release of CXCL2 (PubMed:22879591). {ECO:0000269|PubMed:16637646, ECO:0000269|PubMed:18818205, ECO:0000269|PubMed:22...
FUNCTION: Binds to bacterial lipopolysaccharides (LPS) and has antibacterial activity (PubMed:16637646, PubMed:18818205). Acts via neutrophil N-formyl peptide receptors to enhance the release of CXCL2 (PubMed:22879591). {ECO:0000269|PubMed:16637646, ECO:0000269|PubMed:18818205, ECO:0000269|PubMed:22879591}.
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GO - Biological processes (BP):
antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopoly...
antibacterial humoral response [GO:0019731]; antifungal humoral response [GO:0019732]; antimicrobial humoral immune response mediated by antimicrobial peptide [GO:0061844]; cellular response to interleukin-1 [GO:0071347]; cellular response to interleukin-6 [GO:0071354]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to peptidoglycan [GO:0071224]; cellular response to tumor necrosis factor [GO:0071356]; chronic inflammatory response [GO:0002544]; cytolysis by host of symbiont cells [GO:0051838]; defense response to bacterium [GO:0042742]; defense response to Gram-negative bacterium [GO:0050829]; defense response to Gram-positive bacterium [GO:0050830]; innate immune response [GO:0045087]; innate immune response in mucosa [GO:0002227]; killing by host of symbiont cells [GO:0051873]; modulation of process of another organism [GO:0035821]; neutrophil activation [GO:0042119]; positive regulation of angiogenesis [GO:0045766]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of interleukin-8 production [GO:0032757]; positive regulation of protein phosphorylation [GO:0001934]; response to yeast [GO:0001878]
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GO - Molecular function (MF):
lipopolysaccharide binding [GO:0001530]...
lipopolysaccharide binding [GO:0001530]
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GO - Cellular component (CC):
cell projection [GO:0042995]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule [GO:0042581]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]...
cell projection [GO:0042995]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; extracellular space [GO:0005615]; specific granule [GO:0042581]; specific granule lumen [GO:0035580]; tertiary granule lumen [GO:1904724]
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CAMP
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Kaplan plot for CAMP in
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*NOTE: the Kaplan plots were collected from OncoLnc