DegronMD

Uniprot ID: P49913

Source protein: Cathelicidin antimicrobial peptide

Source gene: CAMP

Class: DEG_APCC_DBOX_1

Location: 11:19

E3 ligase: APC,CDC20,FZR1

DEGRON score: 0.6778

ASA_SCORE: 67.9667

COIL: 0.0549

CONS_SCORE: 0.6697

DSS_SCORE: 0.0072

HELIX: 0.9416

FCONS_SCORE: 1.5653

RIG_SCORE: 0.9431

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.G10D	SIDM02059	Colorectal Carcinoma	GDSC	GRWSLVLLL	DEG_APCC_DBOX_1	0.3056
p.R15Q	SIDM00621	Ewing's Sarcoma	GDSC	GRWSLVLLL	DEG_APCC_DBOX_1	0.7329
p.R15Q	SIDM00490	Glioma	GDSC	GRWSLVLLL	DEG_APCC_DBOX_1	0.7329
p.R15Q	SIDM01749	Osteosarcoma	GDSC	GRWSLVLLL	DEG_APCC_DBOX_1	0.7329

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
P49913	Cathelicidin antimicrobial peptide	DEG_APCC_DBOX_1	11:19	GRWSLVLLL	APC,CDC20,FZR1	0.6778	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons