DegronMD - P51172(SCNN1D)

SCNN1D

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.G784R	TCGA-W3-AA1Q	SKCM	TCGA	PRVMLPGVL	DEG_APCC_DBOX_1	774:782	Mutation rewiring degron network	0.2778
p.E788K	DO225051	BRCA	ICGC	PRVMLPGVL	DEG_APCC_DBOX_1	774:782	Mutation rewiring degron network	0.1667
p.E788K	SIDM02069	Colorectal Carcinoma	GDSC	PRVMLPGVL	DEG_APCC_DBOX_1	774:782	Mutation rewiring degron network	0.1667
p.G770R	DO228483	BRCA	ICGC	PRVMLPGVL	DEG_APCC_DBOX_1	774:782	Mutation rewiring degron network	0.2222
p.G770R	DO230334	COCA	ICGC	PRVMLPGVL	DEG_APCC_DBOX_1	774:782	Mutation rewiring degron network	0.2222
p.G770R	DO229003	COCA	ICGC	PRVMLPGVL	DEG_APCC_DBOX_1	774:782	Mutation rewiring degron network	0.2222
p.G770R	DO229353	LAML	ICGC	PRVMLPGVL	DEG_APCC_DBOX_1	774:782	Mutation rewiring degron network	0.2222
p.V785A	DO229224	THCA	ICGC	PRVMLPGVL	DEG_APCC_DBOX_1	774:782	Mutation rewiring degron network	0.25
p.G784E	SIDM00481	Ovarian Carcinoma	GDSC	PRVMLPGVL	DEG_APCC_DBOX_1	774:782	Mutation rewiring degron network	0.2778
p.G784E	OAW-28	ovary	COSMIC	PRVMLPGVL	DEG_APCC_DBOX_1	774:782	Mutation rewiring degron network	0.2778
p.S786L	SIDM00995	Other Solid Cancers	GDSC	PRVMLPGVL	DEG_APCC_DBOX_1	774:782	Mutation rewiring degron network	0.2222
p.S786L	A431	skin	COSMIC	PRVMLPGVL	DEG_APCC_DBOX_1	774:782	Mutation rewiring degron network	0.2222
p.R775W	SIDM00199	Chondrosarcoma	GDSC	PRVMLPGVL	DEG_APCC_DBOX_1	774:782	Mutation altering degron motif	0.8634
p.M777I	SIDM01689	B-Lymphoblastic Leukemia	GDSC	PRVMLPGVL	DEG_APCC_DBOX_1	774:782	Mutation altering degron motif	0.6507

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*NOTE: the Kaplan plots were collected from OncoLnc