DegronMD - P52294(KPNA1)

KPNA1

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.R10C	TCGA-AA-3984	COAD	TCGA	MTTPGKE	DEG_SCF_FBW7_2	1:7	Mutation rewiring degron network	0.25
p.R10C	DO9002	COAD	ICGC	MTTPGKE	DEG_SCF_FBW7_2	1:7	Mutation rewiring degron network	0.25
p.E7D	TCGA-AP-A1E0	UCEC	TCGA	MTTPGKE	DEG_SCF_FBW7_2	1:7	Mutation altering degron motif	0.6758
p.E7D	TCGA-E6-A1LX	UCEC	TCGA	MTTPGKE	DEG_SCF_FBW7_2	1:7	Mutation altering degron motif	0.6758
p.E7D	TCGA-EO-A3B0	UCEC	TCGA	MTTPGKE	DEG_SCF_FBW7_2	1:7	Mutation altering degron motif	0.6758
p.E7D	DO219773	UCEC	ICGC	MTTPGKE	DEG_SCF_FBW7_2	1:7	Mutation altering degron motif	0.6758
p.E7D	DO41020	UCEC	ICGC	MTTPGKE	DEG_SCF_FBW7_2	1:7	Mutation altering degron motif	0.6758
p.E7D	DO43154	UCEC	ICGC	MTTPGKE	DEG_SCF_FBW7_2	1:7	Mutation altering degron motif	0.6758
p.G5E	TCGA-AX-A2HC	UCEC	TCGA	MTTPGKE	DEG_SCF_FBW7_2	1:7	Mutation altering degron motif	0.6087
p.G5E	DO41572	UCEC	ICGC	MTTPGKE	DEG_SCF_FBW7_2	1:7	Mutation altering degron motif	0.6087
p.G5R	TCGA-GU-A766	BLCA	TCGA	MTTPGKE	DEG_SCF_FBW7_2	1:7	Mutation altering degron motif	0.6457
p.G5R	DO51891	BLCA	ICGC	MTTPGKE	DEG_SCF_FBW7_2	1:7	Mutation altering degron motif	0.6457
p.N16K	DO229018	LICA	ICGC	MTTPGKE	DEG_SCF_FBW7_2	1:7	Mutation rewiring degron network	0.0833
p.K12Q	SIDM00145	T-Lymphoblastic Leukemia	GDSC	MTTPGKE	DEG_SCF_FBW7_2	1:7	Mutation substituting flanking lysine	0.3056
p.K12Q	MOLT-4	haematopoietic and lymphoid tissue	COSMIC	MTTPGKE	DEG_SCF_FBW7_2	1:7	Mutation substituting flanking lysine	0.3056

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*NOTE: the Kaplan plots were collected from OncoLnc