DegronMD - P52738(ZNF140)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.C92F	DO228986	LICA	ICGC	SESSGE	DEG_Kelch_Keap1_1	79:84	Mutation rewiring degron network	0.1111
p.R73I	SIDM01045	Endometrial Carcinoma	GDSC	SESSGE	DEG_Kelch_Keap1_1	79:84	Mutation rewiring degron network	0.1667
p.R73I	EN	endometrium	COSMIC	SESSGE	DEG_Kelch_Keap1_1	79:84	Mutation rewiring degron network	0.1667
p.E70K	SIDM00651	Non-Small Cell Lung Carcinoma	GDSC	SESSGE	DEG_Kelch_Keap1_1	79:84	Mutation rewiring degron network	0.0833
p.E70K	ACH-000980	Lung Cancer	CCLE	SESSGE	DEG_Kelch_Keap1_1	79:84	Mutation rewiring degron network	0.0833
p.E70K	NCI-H1155	lung	COSMIC	SESSGE	DEG_Kelch_Keap1_1	79:84	Mutation rewiring degron network	0.0833
p.A82V	MOLT-13	haematopoietic and lymphoid tissue	COSMIC	SESSGE	DEG_Kelch_Keap1_1	79:84	Mutation altering degron motif	0.6936
p.R74I	EN	endometrium	COSMIC	SESSGE	DEG_Kelch_Keap1_1	79:84	Mutation rewiring degron network	0.1944
p.E71K	NCI-H1155	lung	COSMIC	SESSGE	DEG_Kelch_Keap1_1	79:84	Mutation rewiring degron network	0.1111

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons