DegronMD - P53794(SLC5A3)

SLC5A3

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.N551I	TCGA-A6-3807	COAD	TCGA	VKENC	DEG_APCC_KENBOX_2	554:558	Mutation rewiring degron network	0.25
p.N551I	DO9034	COAD	ICGC	VKENC	DEG_APCC_KENBOX_2	554:558	Mutation rewiring degron network	0.25
p.Q566P	TCGA-CA-6718	COAD	TCGA	VKENC	DEG_APCC_KENBOX_2	554:558	Mutation rewiring degron network	0.1111
p.Q566P	DO7801	COAD	ICGC	VKENC	DEG_APCC_KENBOX_2	554:558	Mutation rewiring degron network	0.1111
p.Q568K	TCGA-GM-A3XL	BRCA	TCGA	VKENC	DEG_APCC_KENBOX_2	554:558	Mutation rewiring degron network	0.0556
p.Q568K	DO44111	BRCA	ICGC	VKENC	DEG_APCC_KENBOX_2	554:558	Mutation rewiring degron network	0.0556
p.Q566K	DO229010	COCA	ICGC	VKENC	DEG_APCC_KENBOX_2	554:558	Mutation rewiring degron network	0.1111
p.Q566K	DO229013	COCA	ICGC	VKENC	DEG_APCC_KENBOX_2	554:558	Mutation rewiring degron network	0.1111
p.Q566K	DO229016	COCA	ICGC	VKENC	DEG_APCC_KENBOX_2	554:558	Mutation rewiring degron network	0.1111
p.Q566K	DO229003	COCA	ICGC	VKENC	DEG_APCC_KENBOX_2	554:558	Mutation rewiring degron network	0.1111
p.Q566K	DO229005	COCA	ICGC	VKENC	DEG_APCC_KENBOX_2	554:558	Mutation rewiring degron network	0.1111
p.W547C	DO228948	LICA	ICGC	VKENC	DEG_APCC_KENBOX_2	554:558	Mutation rewiring degron network	0.1389
p.E556K	DO48909	PBCA	ICGC	VKENC	DEG_APCC_KENBOX_2	554:558	Mutation altering degron motif	0.7022

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*NOTE: the Kaplan plots were collected from OncoLnc