DegronMD - P55259(GP2)

GP2

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.L469I	TCGA-05-4396	LUAD	TCGA	VFLHCE	LIG_APCC_ABBA_1	457:462	Mutation rewiring degron network	0.1389
p.M447V	TCGA-43-6143	LUSC	TCGA	VFLHCE	LIG_APCC_ABBA_1	457:462	Mutation rewiring degron network	0.0556
p.H453Q	TCGA-A5-A2K5	UCEC	TCGA	VFLHCE	LIG_APCC_ABBA_1	457:462	Mutation rewiring degron network	0.2222
p.S468Y	TCGA-BS-A0UF	UCEC	TCGA	VFLHCE	LIG_APCC_ABBA_1	457:462	Mutation rewiring degron network	0.1667
p.E462K	TCGA-IN-A6RP	STAD	TCGA	VFLHCE	LIG_APCC_ABBA_1	457:462	Mutation altering degron motif	0.7022
p.L459R	TCGA-YG-AA3O	SKCM	TCGA	VFLHCE	LIG_APCC_ABBA_1	457:462	Mutation altering degron motif	0.8428
p.L466I	DO23838	LUAD	ICGC	VFLHCE	LIG_APCC_ABBA_1	457:462	Mutation rewiring degron network	0.2222
p.F458L	SIDM01206	Neuroblastoma	GDSC	VFLHCE	LIG_APCC_ABBA_1	457:462	Mutation altering degron motif	0.587
p.F458L	ACH-000310	Neuroblastoma	CCLE	VFLHCE	LIG_APCC_ABBA_1	457:462	Mutation altering degron motif	0.587
p.F458L	ACH-002248	Neuroblastoma	CCLE	VFLHCE	LIG_APCC_ABBA_1	457:462	Mutation altering degron motif	0.587
p.F458L	IMR-5	autonomic ganglia	COSMIC	VFLHCE	LIG_APCC_ABBA_1	457:462	Mutation altering degron motif	0.587
p.F455L	IMR-5	autonomic ganglia	COSMIC	VFLHCE	LIG_APCC_ABBA_1	457:462	Mutation rewiring degron network	0.2778

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*NOTE: the Kaplan plots were collected from OncoLnc