DegronMD - P55957(BID)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.E34K	TCGA-70-6722	LUSC	TCGA	FRRELDALG	DEG_APCC_DBOX_1	33:41	Mutation altering degron motif	0.7022
p.E34K	DO27755	LUSC	ICGC	FRRELDALG	DEG_APCC_DBOX_1	33:41	Mutation altering degron motif	0.7022
p.C49Y	TCGA-AA-3492	COAD	TCGA	FRRELDALG	DEG_APCC_DBOX_1	33:41	Mutation rewiring degron network	0.1111
p.E50D	TCGA-CQ-6227	HNSC	TCGA	FRRELDALG	DEG_APCC_DBOX_1	33:41	Mutation rewiring degron network	0.0833
p.S40R	TCGA-DX-A6YV	SARC	TCGA	FRRELDALG	DEG_APCC_DBOX_1	33:41	Mutation altering degron motif	0.7427
p.R42C	TCGA-FI-A2D0	UCEC	TCGA	FRRELDALG	DEG_APCC_DBOX_1	33:41	Mutation rewiring degron network	0.3056
p.R39Q	DO222427	BTCA	ICGC	FRRELDALG	DEG_APCC_DBOX_1	33:41	Mutation altering degron motif	0.7329
p.A39T	DO44440	HNSC	ICGC	FRRELDALG	DEG_APCC_DBOX_1	33:41	Mutation altering degron motif	0.6028
p.D38E	DO229025	LICA	ICGC	FRRELDALG	DEG_APCC_DBOX_1	33:41	Mutation altering degron motif	0.5647
p.P45T	DO229027	LICA	ICGC	FRRELDALG	DEG_APCC_DBOX_1	33:41	Mutation rewiring degron network	0.2222
p.P45T	DO229045	LICA	ICGC	FRRELDALG	DEG_APCC_DBOX_1	33:41	Mutation rewiring degron network	0.2222
p.E43K	DO36881	READ	ICGC	FRRELDALG	DEG_APCC_DBOX_1	33:41	Mutation rewiring degron network	0.2778
p.P49S	DO51298	SKCM	ICGC	FRRELDALG	DEG_APCC_DBOX_1	33:41	Mutation rewiring degron network	0.1111
p.L40P	DO219784	UCEC	ICGC	FRRELDALG	DEG_APCC_DBOX_1	33:41	Mutation altering degron motif	0.7582
p.R42H	SIDM00238	Ovarian Carcinoma	GDSC	FRRELDALG	DEG_APCC_DBOX_1	33:41	Mutation rewiring degron network	0.3056
p.R42H	OVK-18	ovary	COSMIC	FRRELDALG	DEG_APCC_DBOX_1	33:41	Mutation rewiring degron network	0.3056
p.V46A	OVMIU	ovary	COSMIC	FRRELDALG	DEG_APCC_DBOX_1	33:41	Mutation rewiring degron network	0.1944

Kaplan plot for BID in

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

BID

UniProt ID: P55957

Entrez ID: 637

Protein name: BH3-interacting domain death agonist (p22 BID) (BID) [Cleaved into: BH3-interacting domain death agonist p15 (p15 BID); BH3-interacting domain death agonist p13 (p13 BID); BH3-interacting domain death agonist p11 (p11 BID)]

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for BID in