DegronMD - P56177(DLX1)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.G223V	TCGA-85-6561	LUSC	TCGA	PNSSS	DEG_SPOP_SBC_1	218:222	Mutation rewiring degron network	0.3056
p.G223V	DO26518	LUSC	ICGC	PNSSS	DEG_SPOP_SBC_1	218:222	Mutation rewiring degron network	0.3056
p.G228E	TCGA-EE-A2GI	SKCM	TCGA	PNSSS	DEG_SPOP_SBC_1	218:222	Mutation rewiring degron network	0.1667
p.G228E	DO37410	SKCM	ICGC	PNSSS	DEG_SPOP_SBC_1	218:222	Mutation rewiring degron network	0.1667
p.N219T	TCGA-EO-A3B0	UCEC	TCGA	PNSSS	DEG_SPOP_SBC_1	218:222	Mutation altering degron motif	0.5944
p.N219T	DO219773	UCEC	ICGC	PNSSS	DEG_SPOP_SBC_1	218:222	Mutation altering degron motif	0.5944
p.G223E	TCGA-FD-A5BT	BLCA	TCGA	PNSSS	DEG_SPOP_SBC_1	218:222	Mutation rewiring degron network	0.3056
p.G223E	DO44032	BLCA	ICGC	PNSSS	DEG_SPOP_SBC_1	218:222	Mutation rewiring degron network	0.3056
p.P210S	TCGA-RP-A695	SKCM	TCGA	PNSSS	DEG_SPOP_SBC_1	218:222	Mutation rewiring degron network	0.1111
p.P210S	DO51270	SKCM	ICGC	PNSSS	DEG_SPOP_SBC_1	218:222	Mutation rewiring degron network	0.1111
p.S232F	DO229453	SKCA	ICGC	PNSSS	DEG_SPOP_SBC_1	218:222	Mutation rewiring degron network	0.0556
p.P213L	SIDM01007	T-Lymphoblastic Leukemia	GDSC	PNSSS	DEG_SPOP_SBC_1	218:222	Mutation rewiring degron network	0.1944
p.P213L	ACH-002256	Leukemia	CCLE	PNSSS	DEG_SPOP_SBC_1	218:222	Mutation rewiring degron network	0.1944
p.P213L	KARPAS-45	haematopoietic and lymphoid tissue	COSMIC	PNSSS	DEG_SPOP_SBC_1	218:222	Mutation rewiring degron network	0.1944
p.P214T	SIDM00333	Endometrial Carcinoma	GDSC	PNSSS	DEG_SPOP_SBC_1	218:222	Mutation rewiring degron network	0.2222
p.P214T	ACH-000988	Endometrial/Uterine Cancer	CCLE	PNSSS	DEG_SPOP_SBC_1	218:222	Mutation rewiring degron network	0.2222
p.P214T	MFE-319	endometrium	COSMIC	PNSSS	DEG_SPOP_SBC_1	218:222	Mutation rewiring degron network	0.2222

Kaplan plot for DLX1 in

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

DLX1

UniProt ID: P56177

Entrez ID: 1745

Protein name: Homeobox protein DLX-1

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for DLX1 in