DegronMD - P57054(PIGP)

PIGP

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.T6I	TCGA-CL-5917	READ	TCGA	PRSTS	DEG_SPOP_SBC_1	3:7	Mutation altering degron motif	0.8189
p.T6I	DO36560	READ	ICGC	PRSTS	DEG_SPOP_SBC_1	3:7	Mutation altering degron motif	0.8189
p.T6P	TCGA-WB-A815	PCPG	TCGA	PRSTS	DEG_SPOP_SBC_1	3:7	Mutation altering degron motif	0.8142
p.A9T	DO229010	COCA	ICGC	PRSTS	DEG_SPOP_SBC_1	3:7	Mutation blocking phosphorylation signal	0.7222
p.A9T	DO229013	COCA	ICGC	PRSTS	DEG_SPOP_SBC_1	3:7	Mutation blocking phosphorylation signal	0.7222
p.A9T	DO229016	COCA	ICGC	PRSTS	DEG_SPOP_SBC_1	3:7	Mutation blocking phosphorylation signal	0.7222
p.A9T	DO229003	COCA	ICGC	PRSTS	DEG_SPOP_SBC_1	3:7	Mutation blocking phosphorylation signal	0.7222
p.A9T	DO229005	COCA	ICGC	PRSTS	DEG_SPOP_SBC_1	3:7	Mutation blocking phosphorylation signal	0.7222
p.L14F	DO11854	GBM	ICGC	PRSTS	DEG_SPOP_SBC_1	3:7	Mutation rewiring degron network	0.1389
p.S5R	DO229038	LICA	ICGC	PRSTS	DEG_SPOP_SBC_1	3:7	Mutation altering degron motif	0.7427
p.P10T	DO229006	LICA	ICGC	PRSTS	DEG_SPOP_SBC_1	3:7	Mutation rewiring degron network	0.25
p.P6T	DO229008	LICA	ICGC	PRSTS	DEG_SPOP_SBC_1	3:7	Mutation altering degron motif	0.7031
p.N4H	DO52412	UCEC	ICGC	PRSTS	DEG_SPOP_SBC_1	3:7	Mutation altering degron motif	0.7423
p.R12T	ACH-000799	Skin Cancer	CCLE	PRSTS	DEG_SPOP_SBC_1	3:7	Mutation rewiring degron network	0.1944
p.I10F	SK-MEL-24	skin	COSMIC	PRSTS	DEG_SPOP_SBC_1	3:7	Mutation rewiring degron network	0.25

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*NOTE: the Kaplan plots were collected from OncoLnc