DegronMD - P57740(NUP107)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.E143D	TCGA-CG-4305	STAD	TCGA	MSMFSD	LIG_APCC_ABBA_1	152:157	Mutation rewiring degron network	0.0833
p.M152I	TCGA-FD-A6TG	BLCA	TCGA	MSMFSD	LIG_APCC_ABBA_1	152:157	Mutation altering degron motif	0.6507
p.R166H	DO51883	BLCA	ICGC	MSMFSD	LIG_APCC_ABBA_1	152:157	Mutation rewiring degron network	0.0833
p.R166H	SNU-398	liver	COSMIC	MSMFSD	LIG_APCC_ABBA_1	152:157	Mutation rewiring degron network	0.0833
p.V162I	DO44178	BRCA	ICGC	MSMFSD	LIG_APCC_ABBA_1	152:157	Mutation rewiring degron network	0.1944
p.H151Y	DO234230	ESAD	ICGC	MSMFSD	LIG_APCC_ABBA_1	152:157	Mutation rewiring degron network	0.3056
p.V165F	DO229045	LICA	ICGC	MSMFSD	LIG_APCC_ABBA_1	152:157	Mutation rewiring degron network	0.1111
p.E147D	DO45035	LINC	ICGC	MSMFSD	LIG_APCC_ABBA_1	152:157	Mutation rewiring degron network	0.1944
p.T149A	DO24218	LUAD	ICGC	MSMFSD	LIG_APCC_ABBA_1	152:157	Mutation rewiring degron network	0.25
p.R166C	DO222415	MELA	ICGC	MSMFSD	LIG_APCC_ABBA_1	152:157	Mutation rewiring degron network	0.0833
p.R156L	DO28923	OV	ICGC	MSMFSD	LIG_APCC_ABBA_1	152:157	Mutation altering degron motif	0.8428
p.R156L	HCC1428	breast	COSMIC	MSMFSD	LIG_APCC_ABBA_1	152:157	Mutation altering degron motif	0.8428
p.T149N	DO51407	PRAD	ICGC	MSMFSD	LIG_APCC_ABBA_1	152:157	Mutation rewiring degron network	0.25
p.M152V	SIDM00217	Colorectal Carcinoma	GDSC	MSMFSD	LIG_APCC_ABBA_1	152:157	Mutation altering degron motif	0.6097
p.F155L	SIDM00217	Colorectal Carcinoma	GDSC	MSMFSD	LIG_APCC_ABBA_1	152:157	Mutation altering degron motif	0.6981
p.Q155H	HCT-15	large intestine	COSMIC	MSMFSD	LIG_APCC_ABBA_1	152:157	Mutation altering degron motif	0.7582
p.P167L	TMK-1	stomach	COSMIC	MSMFSD	LIG_APCC_ABBA_1	152:157	Mutation rewiring degron network	0.0556

Kaplan plot for NUP107 in

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

NUP107

UniProt ID: P57740

Entrez ID: 57122

Protein name: Nuclear pore complex protein Nup107 (107 kDa nucleoporin) (Nucleoporin Nup107)

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for NUP107 in