DegronMD - P58505(C21orf58)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.I199T	TCGA-AD-A5EJ	COAD	TCGA	PRIILPTVP	DEG_APCC_DBOX_1	197:205	Mutation altering degron motif	0.5966
p.T203M	TCGA-B5-A3FC	UCEC	TCGA	PRIILPTVP	DEG_APCC_DBOX_1	197:205	Mutation altering degron motif	0.6312
p.P197Q	DO228974	LICA	ICGC	PRIILPTVP	DEG_APCC_DBOX_1	197:205	Mutation altering degron motif	0.5924
p.Q205H	DO232761	PBCA	ICGC	PRIILPTVP	DEG_APCC_DBOX_1	197:205	Mutation altering degron motif	0.7582
p.Q205L	ACH-000544	Esophageal Cancer	CCLE	PRIILPTVP	DEG_APCC_DBOX_1	197:205	Mutation altering degron motif	0.7765

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons