DegronMD - P62263(RPS14)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.P136S	TCGA-FR-A726	SKCM	TCGA	VTPIPS	DEG_SCF_FBW7_1	132:137	Mutation altering degron motif	0.5641
p.P136S	DO48665	SKCM	ICGC	VTPIPS	DEG_SCF_FBW7_1	132:137	Mutation altering degron motif	0.5641
p.P136S	SIDM00545	Melanoma	GDSC	VTPIPS	DEG_SCF_FBW7_1	132:137	Mutation altering degron motif	0.5641
p.P136S	ACH-000987	Skin Cancer	CCLE	VTPIPS	DEG_SCF_FBW7_1	132:137	Mutation altering degron motif	0.5641
p.P136S	Mewo	skin	COSMIC	VTPIPS	DEG_SCF_FBW7_1	132:137	Mutation altering degron motif	0.5641
p.R128W	TCGA-VS-A9UJ	CESC	TCGA	VTPIPS	DEG_SCF_FBW7_1	132:137	Mutation rewiring degron network	0.2222
p.R128W	DO219735	CESC	ICGC	VTPIPS	DEG_SCF_FBW7_1	132:137	Mutation rewiring degron network	0.2222
p.R128W	DO230323	COCA	ICGC	VTPIPS	DEG_SCF_FBW7_1	132:137	Mutation rewiring degron network	0.2222
p.V132D	DO27831	MALY	ICGC	VTPIPS	DEG_SCF_FBW7_1	132:137	Mutation altering degron motif	0.7785
p.R141H	DO49138	PACA	ICGC	VTPIPS	DEG_SCF_FBW7_1	132:137	Mutation rewiring degron network	0.2222
p.R147C	SIDM00777	Colorectal Carcinoma	GDSC	VTPIPS	DEG_SCF_FBW7_1	132:137	Mutation rewiring degron network	0.0556
p.R147C	ACH-000360	Colon/Colorectal Cancer	CCLE	VTPIPS	DEG_SCF_FBW7_1	132:137	Mutation rewiring degron network	0.0556
p.R147C	NCI-H508	large intestine	COSMIC	VTPIPS	DEG_SCF_FBW7_1	132:137	Mutation rewiring degron network	0.0556

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons