DegronMD - P62906(RPL10A)

RPL10A

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.K27T	TCGA-D3-A5GU	SKCM	TCGA	RRKFLETVE	DEG_APCC_DBOX_1	25:33	Mutation altering degron motif	0.6195
p.L38F	TCGA-EM-A3AQ	THCA	TCGA	RRKFLETVE	DEG_APCC_DBOX_1	25:33	Mutation rewiring degron network	0.1944
p.L38F	DO40484	THCA	ICGC	RRKFLETVE	DEG_APCC_DBOX_1	25:33	Mutation rewiring degron network	0.1944
p.P43S	TCGA-TS-A7P6	MESO	TCGA	RRKFLETVE	DEG_APCC_DBOX_1	25:33	Mutation rewiring degron network	0.0556
p.P43H	TCGA-VQ-A8P2	STAD	TCGA	RRKFLETVE	DEG_APCC_DBOX_1	25:33	Mutation rewiring degron network	0.0556
p.P43H	DO51761	STAD	ICGC	RRKFLETVE	DEG_APCC_DBOX_1	25:33	Mutation rewiring degron network	0.0556
p.D42H	DO225004	BRCA	ICGC	RRKFLETVE	DEG_APCC_DBOX_1	25:33	Mutation rewiring degron network	0.0833
p.R25H	DO6394	CLLE	ICGC	RRKFLETVE	DEG_APCC_DBOX_1	25:33	Mutation altering degron motif	0.7133
p.G20W	DO231215	LAML	ICGC	RRKFLETVE	DEG_APCC_DBOX_1	25:33	Mutation rewiring degron network	0.1944
p.V17G	DO50760	LICA	ICGC	RRKFLETVE	DEG_APCC_DBOX_1	25:33	Mutation rewiring degron network	0.1111
p.S37T	DO27855	MALY	ICGC	RRKFLETVE	DEG_APCC_DBOX_1	25:33	Mutation rewiring degron network	0.2222
p.N40K	SU-DHL-5	haematopoietic and lymphoid tissue	COSMIC	RRKFLETVE	DEG_APCC_DBOX_1	25:33	Mutation rewiring degron network	0.1389

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*NOTE: the Kaplan plots were collected from OncoLnc