DegronMD - P63151(PPP2R2A)

PPP2R2A

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.A433V	TCGA-24-1552	OV	TCGA	PKENI	DEG_APCC_KENBOX_2	426:430	Mutation rewiring degron network	0.25
p.A433V	DO31551	OV	ICGC	PKENI	DEG_APCC_KENBOX_2	426:430	Mutation rewiring degron network	0.25
p.S419I	TCGA-A5-A0G2	UCEC	TCGA	PKENI	DEG_APCC_KENBOX_2	426:430	Mutation rewiring degron network	0.1389
p.S419I	DO41235	UCEC	ICGC	PKENI	DEG_APCC_KENBOX_2	426:430	Mutation rewiring degron network	0.1389
p.K427T	TCGA-CA-6717	COAD	TCGA	PKENI	DEG_APCC_KENBOX_2	426:430	Mutation altering degron motif	0.7306
p.K427T	DO8264	COAD	ICGC	PKENI	DEG_APCC_KENBOX_2	426:430	Mutation altering degron motif	0.7306
p.D424H	TCGA-DX-AB2W	SARC	TCGA	PKENI	DEG_APCC_KENBOX_2	426:430	Mutation rewiring degron network	0.2778
p.D424H	DO220095	SARC	ICGC	PKENI	DEG_APCC_KENBOX_2	426:430	Mutation rewiring degron network	0.2778
p.A433S	DO229019	LICA	ICGC	PKENI	DEG_APCC_KENBOX_2	426:430	Mutation rewiring degron network	0.25
p.V433I	ACH-001669	Leukemia	CCLE	PKENI	DEG_APCC_KENBOX_2	426:430	Mutation rewiring degron network	0.25
p.V433I	ACH-002238	Leukemia	CCLE	PKENI	DEG_APCC_KENBOX_2	426:430	Mutation rewiring degron network	0.25
p.V433I	GR-ST	haematopoietic and lymphoid tissue	COSMIC	PKENI	DEG_APCC_KENBOX_2	426:430	Mutation rewiring degron network	0.25

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*NOTE: the Kaplan plots were collected from OncoLnc