DegronMD - P78368(CSNK1G2)

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GO - Molecular function (MF): View more >>

GO - Cellular component (CC): View more >>

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.V341I	TCGA-B5-A11U	UCEC	TCGA	PLPTPIGT	DEG_SCF_FBW7_1	333:340	Mutation rewiring degron network	0.3056
p.V341I	DO40804	UCEC	ICGC	PLPTPIGT	DEG_SCF_FBW7_1	333:340	Mutation rewiring degron network	0.3056
p.Y327H	TCGA-DI-A1BU	UCEC	TCGA	PLPTPIGT	DEG_SCF_FBW7_1	333:340	Mutation rewiring degron network	0.1667
p.Y327H	DO42023	UCEC	ICGC	PLPTPIGT	DEG_SCF_FBW7_1	333:340	Mutation rewiring degron network	0.1667
p.H342Y	DO222731	MELA	ICGC	PLPTPIGT	DEG_SCF_FBW7_1	333:340	Mutation rewiring degron network	0.2778
p.T343I	ACH-000941	Endometrial/Uterine Cancer	CCLE	PLPTPIGT	DEG_SCF_FBW7_1	333:340	Mutation rewiring degron network	0.25

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons