DegronMD - P81877(SSBP2)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.M213I	TCGA-D3-A3ML	SKCM	TCGA	MRPPLNALG	DEG_APCC_DBOX_1	196:204	Mutation rewiring degron network	0.0833
p.M213I	DO47413	SKCM	ICGC	MRPPLNALG	DEG_APCC_DBOX_1	196:204	Mutation rewiring degron network	0.0833
p.G210V	TCGA-EE-A2MS	SKCM	TCGA	MRPPLNALG	DEG_APCC_DBOX_1	196:204	Mutation rewiring degron network	0.1667
p.G210V	DO37567	SKCM	ICGC	MRPPLNALG	DEG_APCC_DBOX_1	196:204	Mutation rewiring degron network	0.1667
p.P198H	TCGA-FS-A1ZU	SKCM	TCGA	MRPPLNALG	DEG_APCC_DBOX_1	196:204	Mutation altering degron motif	0.6583
p.P206H	TCGA-IB-7651	PAAD	TCGA	MRPPLNALG	DEG_APCC_DBOX_1	196:204	Mutation rewiring degron network	0.2778
p.P206H	DO46657	PAAD	ICGC	MRPPLNALG	DEG_APCC_DBOX_1	196:204	Mutation rewiring degron network	0.2778
p.M186I	DO8264	COAD	ICGC	MRPPLNALG	DEG_APCC_DBOX_1	196:204	Mutation rewiring degron network	0.0556
p.M186I	ONS-76	central nervous system	COSMIC	MRPPLNALG	DEG_APCC_DBOX_1	196:204	Mutation rewiring degron network	0.0556
p.G205D	DO233869	GACA	ICGC	MRPPLNALG	DEG_APCC_DBOX_1	196:204	Mutation rewiring degron network	0.3056
p.P206T	DO222562	MELA	ICGC	MRPPLNALG	DEG_APCC_DBOX_1	196:204	Mutation rewiring degron network	0.2778
p.G210E	DO232761	PBCA	ICGC	MRPPLNALG	DEG_APCC_DBOX_1	196:204	Mutation rewiring degron network	0.1667
p.Q190H	SIDM00282	Colorectal Carcinoma	GDSC	MRPPLNALG	DEG_APCC_DBOX_1	196:204	Mutation rewiring degron network	0.1667
p.Q190H	CW-2	large intestine	COSMIC	MRPPLNALG	DEG_APCC_DBOX_1	196:204	Mutation rewiring degron network	0.1667
p.M208I	ACH-000776	Brain Cancer	CCLE	MRPPLNALG	DEG_APCC_DBOX_1	196:204	Mutation rewiring degron network	0.2222
p.M208I	ONS-76	central nervous system	COSMIC	MRPPLNALG	DEG_APCC_DBOX_1	196:204	Mutation rewiring degron network	0.2222
p.A205P	NCI-H1755	lung	COSMIC	MRPPLNALG	DEG_APCC_DBOX_1	196:204	Mutation rewiring degron network	0.3056
p.A197P	NCI-H1755	lung	COSMIC	MRPPLNALG	DEG_APCC_DBOX_1	196:204	Mutation altering degron motif	0.7503
p.A207P	NCI-H1755	lung	COSMIC	MRPPLNALG	DEG_APCC_DBOX_1	196:204	Mutation rewiring degron network	0.25
p.P214T	RF-48	stomach	COSMIC	MRPPLNALG	DEG_APCC_DBOX_1	196:204	Mutation rewiring degron network	0.0556
p.M188I	ONS-76	central nervous system	COSMIC	MRPPLNALG	DEG_APCC_DBOX_1	196:204	Mutation rewiring degron network	0.1111

Kaplan plot for SSBP2 in

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

SSBP2

UniProt ID: P81877

Entrez ID: 23635

Protein name: Single-stranded DNA-binding protein 2 (Sequence-specific single-stranded-DNA-binding protein 2)

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for SSBP2 in