DegronMD - P82914(MRPS15)

MRPS15

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.T205A	TCGA-AD-A5EJ	COAD	TCGA	PPLY	ITCH	192:195	Mutation rewiring degron network	0.0556
p.T205A	DO50090	COAD	ICGC	PPLY	ITCH	192:195	Mutation rewiring degron network	0.0556
p.P193S	TCGA-AZ-4615	COAD	TCGA	PPLY	ITCH	192:195	Mutation altering degron motif	0.6752
p.P193S	DO7977	COAD	ICGC	PPLY	ITCH	192:195	Mutation altering degron motif	0.6752
p.R201S	TCGA-DA-A1IB	SKCM	TCGA	PPLY	ITCH	192:195	Mutation rewiring degron network	0.1667
p.R201S	DO38033	SKCM	ICGC	PPLY	ITCH	192:195	Mutation rewiring degron network	0.1667
p.Y189C	TCGA-NH-A5IV	COAD	TCGA	PPLY	ITCH	192:195	Mutation blocking phosphorylation signal	0.6944
p.Y189C	DO49095	COAD	ICGC	PPLY	ITCH	192:195	Mutation blocking phosphorylation signal	0.6944
p.P192S	DO230336	COCA	ICGC	PPLY	ITCH	192:195	Mutation altering degron motif	0.6752
p.R202Q	DO233739	GACA	ICGC	PPLY	ITCH	192:195	Mutation rewiring degron network	0.1389
p.R202Q	DO229250	THCA	ICGC	PPLY	ITCH	192:195	Mutation rewiring degron network	0.1389
p.P193A	SIDM00534	Colorectal Carcinoma	GDSC	PPLY	ITCH	192:195	Mutation altering degron motif	0.7503
p.P193A	HT-115	large intestine	COSMIC	PPLY	ITCH	192:195	Mutation altering degron motif	0.7503
p.F191S	ACH-000780	Lung Cancer	CCLE	PPLY	ITCH	192:195	Mutation rewiring degron network	0.3056

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*NOTE: the Kaplan plots were collected from OncoLnc