DegronMD - P98196(ATP11A)

ATP11A

UniProt ID: P98196

Entrez ID: 23250

Protein name: Phospholipid-transporting ATPase IH (EC 7.6.2.1) (ATPase IS) (ATPase class VI type 11A) (P4-ATPase flippase complex alpha subunit ATP11A)

External links: UniprotKB HGNC RefSeq COSMIC

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GO - Cellular component (CC): View more >>

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.V227M	TCGA-75-5122	LUAD	TCGA	RINVYSD	LIG_APCC_ABBAyCdc20_2	229:235	Mutation rewiring degron network	0.2778
p.V227M	TCGA-AJ-A3BH	UCEC	TCGA	RINVYSD	LIG_APCC_ABBAyCdc20_2	229:235	Mutation rewiring degron network	0.2778
p.V227M	TCGA-QS-A8F1	UCEC	TCGA	RINVYSD	LIG_APCC_ABBAyCdc20_2	229:235	Mutation rewiring degron network	0.2778
p.V227M	DO233207	GACA	ICGC	RINVYSD	LIG_APCC_ABBAyCdc20_2	229:235	Mutation rewiring degron network	0.2778
p.V227M	DO23882	LUAD	ICGC	RINVYSD	LIG_APCC_ABBAyCdc20_2	229:235	Mutation rewiring degron network	0.2778
p.V227M	DO219783	UCEC	ICGC	RINVYSD	LIG_APCC_ABBAyCdc20_2	229:235	Mutation rewiring degron network	0.2778
p.V227M	DO41638	UCEC	ICGC	RINVYSD	LIG_APCC_ABBAyCdc20_2	229:235	Mutation rewiring degron network	0.2778
p.V232I	TCGA-A5-A1OF	UCEC	TCGA	RINVYSD	LIG_APCC_ABBAyCdc20_2	229:235	Mutation altering degron motif	0.5965
p.V232I	DO42568	UCEC	ICGC	RINVYSD	LIG_APCC_ABBAyCdc20_2	229:235	Mutation altering degron motif	0.5965
p.R229H	TCGA-E2-A10B	BRCA	TCGA	RINVYSD	LIG_APCC_ABBAyCdc20_2	229:235	Mutation altering degron motif	0.8244
p.R229H	DO5843	BRCA	ICGC	RINVYSD	LIG_APCC_ABBAyCdc20_2	229:235	Mutation altering degron motif	0.8244
p.R229C	TCGA-EE-A2MR	SKCM	TCGA	RINVYSD	LIG_APCC_ABBAyCdc20_2	229:235	Mutation altering degron motif	0.8301
p.R229C	DO232224	PBCA	ICGC	RINVYSD	LIG_APCC_ABBAyCdc20_2	229:235	Mutation altering degron motif	0.8301
p.R229C	DO37819	SKCM	ICGC	RINVYSD	LIG_APCC_ABBAyCdc20_2	229:235	Mutation altering degron motif	0.8301
p.R242G	DO222637	BTCA	ICGC	RINVYSD	LIG_APCC_ABBAyCdc20_2	229:235	Mutation rewiring degron network	0.1389
p.G245E	DO233237	GACA	ICGC	RINVYSD	LIG_APCC_ABBAyCdc20_2	229:235	Mutation rewiring degron network	0.0556
p.V241L	DO228974	LICA	ICGC	RINVYSD	LIG_APCC_ABBAyCdc20_2	229:235	Mutation rewiring degron network	0.1667
p.R229L	DO228976	LICA	ICGC	RINVYSD	LIG_APCC_ABBAyCdc20_2	229:235	Mutation altering degron motif	0.8428
p.V227L	DO228978	LICA	ICGC	RINVYSD	LIG_APCC_ABBAyCdc20_2	229:235	Mutation rewiring degron network	0.2778

Kaplan plot for ATP11A in

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*NOTE: the Kaplan plots were collected from OncoLnc