DegronMD - Q01954(BNC1)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.T446M	TCGA-2W-A8YY	CESC	TCGA	PPSY	ITCH	453:456	Mutation rewiring degron network	0.1389
p.T446M	TCGA-BQ-7044	KIRP	TCGA	PPSY	ITCH	453:456	Mutation rewiring degron network	0.1389
p.T446M	DO223732	CESC	ICGC	PPSY	ITCH	453:456	Mutation rewiring degron network	0.1389
p.T446M	DO20942	KIRP	ICGC	PPSY	ITCH	453:456	Mutation rewiring degron network	0.1389
p.Q81P	TCGA-A5-A1OF	UCEC	TCGA	PPMY	ITCH	74:77	Mutation rewiring degron network	0.2222
p.Q81P	DO42568	UCEC	ICGC	PPMY	ITCH	74:77	Mutation rewiring degron network	0.2222
p.P74H	TCGA-CM-5864	COAD	TCGA	PPMY	ITCH	74:77	Mutation altering degron motif	0.7694
p.P74H	DO8690	COAD	ICGC	PPMY	ITCH	74:77	Mutation altering degron motif	0.7694
p.P74S	TCGA-CU-A0YN	BLCA	TCGA	PPMY	ITCH	74:77	Mutation altering degron motif	0.6752
p.P74S	DO488	BLCA	ICGC	PPMY	ITCH	74:77	Mutation altering degron motif	0.6752
p.A67S	TCGA-DF-A2KN	UCEC	TCGA	PPMY	ITCH	74:77	Mutation rewiring degron network	0.1389
p.A67S	DO223282	UCEC	ICGC	PPMY	ITCH	74:77	Mutation rewiring degron network	0.1389
p.P457S	TCGA-EE-A3AE	SKCM	TCGA	PPSY	ITCH	453:456	Mutation rewiring degron network	0.3056
p.P457S	DO37802	SKCM	ICGC	PPSY	ITCH	453:456	Mutation rewiring degron network	0.3056
p.R72G	TCGA-FI-A2F4	UCEC	TCGA	PPMY	ITCH	74:77	Mutation rewiring degron network	0.2778
p.R72G	DO43434	UCEC	ICGC	PPMY	ITCH	74:77	Mutation rewiring degron network	0.2778
p.A65V	TCGA-FR-A726	SKCM	TCGA	PPMY	ITCH	74:77	Mutation rewiring degron network	0.0833
p.A65V	DO48665	SKCM	ICGC	PPMY	ITCH	74:77	Mutation rewiring degron network	0.0833
p.G465A	TCGA-KR-A7K0	LIHC	TCGA	PPSY	ITCH	453:456	Mutation rewiring degron network	0.0833
p.G465A	DO49696	LIHC	ICGC	PPSY	ITCH	453:456	Mutation rewiring degron network	0.0833
p.T446S	TCGA-NJ-A4YQ	LUAD	TCGA	PPSY	ITCH	453:456	Mutation rewiring degron network	0.1389
p.T446S	DO218944	LUAD	ICGC	PPSY	ITCH	453:456	Mutation rewiring degron network	0.1389
p.E83K	TCGA-QB-AA9O	SKCM	TCGA	PPMY	ITCH	74:77	Mutation rewiring degron network	0.1667
p.E83K	DO51267	SKCM	ICGC	PPMY	ITCH	74:77	Mutation rewiring degron network	0.1667
p.C450Y	TCGA-UB-A7MD	LIHC	TCGA	PPSY	ITCH	453:456	Mutation rewiring degron network	0.25
p.C450Y	DO52320	LIHC	ICGC	PPSY	ITCH	453:456	Mutation rewiring degron network	0.25
p.A67T	TCGA-VS-A9U6	CESC	TCGA	PPMY	ITCH	74:77	Mutation rewiring degron network	0.1389
p.A67T	DO219728	CESC	ICGC	PPMY	ITCH	74:77	Mutation rewiring degron network	0.1389
p.A67T	SIDM02059	Colorectal Carcinoma	GDSC	PPMY	ITCH	74:77	Mutation rewiring degron network	0.1389
p.D462N	TCGA-W3-AA1V	SKCM	TCGA	PPSY	ITCH	453:456	Mutation rewiring degron network	0.1667
p.D462N	DO51276	SKCM	ICGC	PPSY	ITCH	453:456	Mutation rewiring degron network	0.1667
p.G460E	DO222843	MELA	ICGC	PPSY	ITCH	453:456	Mutation rewiring degron network	0.2222
p.Q86L	SIDM00425	Ovarian Carcinoma	GDSC	PPMY	ITCH	74:77	Mutation rewiring degron network	0.0833
p.Q86L	OVTOKO	ovary	COSMIC	PPMY	ITCH	74:77	Mutation rewiring degron network	0.0833
p.L68I	SIDM00120	Prostate Carcinoma	GDSC	PPMY	ITCH	74:77	Mutation rewiring degron network	0.1667
p.L68I	DU-145	prostate	COSMIC	PPMY	ITCH	74:77	Mutation rewiring degron network	0.1667
p.P454L	SIDM01175	Other Sarcomas	GDSC	PPSY	ITCH	453:456	Mutation altering degron motif	0.7582
p.P454L	SW684	soft tissue	COSMIC	PPSY	ITCH	453:456	Mutation altering degron motif	0.7582
p.S463F	SIDM00592	Oral Cavity Carcinoma	GDSC	PPSY	ITCH	453:456	Mutation rewiring degron network	0.1389
p.S463F	HO-1-N-1	salivary gland	COSMIC	PPSY	ITCH	453:456	Mutation rewiring degron network	0.1389
p.V445L	SIDM00990	Non-Small Cell Lung Carcinoma	GDSC	PPSY	ITCH	453:456	Mutation rewiring degron network	0.1111
p.V445L	BEN	lung	COSMIC	PPSY	ITCH	453:456	Mutation rewiring degron network	0.1111
p.V83L	ACH-000410	Bone Cancer	CCLE	PPMY	ITCH	74:77	Mutation rewiring degron network	0.1667
p.V83L	Saos-2	bone	COSMIC	PPMY	ITCH	74:77	Mutation rewiring degron network	0.1667
p.Q79L	ACH-000663	Ovarian Cancer	CCLE	PPMY	ITCH	74:77	Mutation rewiring degron network	0.2778
p.Q79L	OVTOKO	ovary	COSMIC	PPMY	ITCH	74:77	Mutation rewiring degron network	0.2778
p.S456F	ACH-002244	Head and Neck Cancer	CCLE	PPSY	ITCH	453:456	Mutation altering degron motif	0.7982
p.S456F	HO-1-N-1	salivary gland	COSMIC	PPSY	ITCH	453:456	Mutation altering degron motif	0.7982
p.P447L	ACH-002309	Sarcoma	CCLE	PPSY	ITCH	453:456	Mutation rewiring degron network	0.1667
p.P447L	SW684	soft tissue	COSMIC	PPSY	ITCH	453:456	Mutation rewiring degron network	0.1667

Kaplan plot for BNC1 in

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

BNC1

UniProt ID: Q01954

Entrez ID: 646

Protein name: Zinc finger protein basonuclin-1

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for BNC1 in