DegronMD - Q02833(RASSF7)

GO - Biological processes (BP): View more >>

GO - Molecular function (MF): View more >>

GO - Cellular component (CC): View more >>

Choose a PDB ID:
Open in full screen with detailed sequence annotations

Data table is loading....

Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.R138C	DO222973	BTCA	ICGC	GPAAPVTPT	DEG_SIAH_1	140:148	Mutation rewiring degron network	0.2778
p.R138C	SIDM00899	Pancreatic Carcinoma	GDSC	GPAAPVTPT	DEG_SIAH_1	140:148	Mutation rewiring degron network	0.2778
p.R138C	SIDM01475	Ovarian Carcinoma	GDSC	GPAAPVTPT	DEG_SIAH_1	140:148	Mutation rewiring degron network	0.2778
p.R138H	DO222765	COCA	ICGC	GPAAPVTPT	DEG_SIAH_1	140:148	Mutation rewiring degron network	0.2778
p.R156Q	DO229013	COCA	ICGC	GPAAPVTPT	DEG_SIAH_1	140:148	Mutation rewiring degron network	0.1111
p.R156Q	DO229016	COCA	ICGC	GPAAPVTPT	DEG_SIAH_1	140:148	Mutation rewiring degron network	0.1111
p.R156Q	DO229473	LAML	ICGC	GPAAPVTPT	DEG_SIAH_1	140:148	Mutation rewiring degron network	0.1111
p.R156Q	DO229489	LAML	ICGC	GPAAPVTPT	DEG_SIAH_1	140:148	Mutation rewiring degron network	0.1111
p.R156Q	DO231104	LUSC	ICGC	GPAAPVTPT	DEG_SIAH_1	140:148	Mutation rewiring degron network	0.1111
p.R156Q	DO231102	LUSC	ICGC	GPAAPVTPT	DEG_SIAH_1	140:148	Mutation rewiring degron network	0.1111
p.A143V	DO33091	PACA	ICGC	GPAAPVTPT	DEG_SIAH_1	140:148	Mutation altering degron motif	0.6936
p.A143V	SIDM01617	Endometrial Carcinoma	GDSC	GPAAPVTPT	DEG_SIAH_1	140:148	Mutation altering degron motif	0.6936
p.A143V	ACH-000994	Endometrial/Uterine Cancer	CCLE	GPAAPVTPT	DEG_SIAH_1	140:148	Mutation altering degron motif	0.6936
p.P149L	DO229272	THCA	ICGC	GPAAPVTPT	DEG_SIAH_1	140:148	Mutation rewiring degron network	0.3056
p.P130L	DO229245	THCA	ICGC	GPAAPVTPT	DEG_SIAH_1	140:148	Mutation rewiring degron network	0.0556
p.A133V	SIDM00085	Glioma	GDSC	GPAAPVTPT	DEG_SIAH_1	140:148	Mutation rewiring degron network	0.1389
p.A133V	ACH-000655	Brain Cancer	CCLE	GPAAPVTPT	DEG_SIAH_1	140:148	Mutation rewiring degron network	0.1389
p.R156P	SIDM01653	Non-Cancerous	GDSC	GPAAPVTPT	DEG_SIAH_1	140:148	Mutation rewiring degron network	0.1111
p.R156P	SIDM00207	Glioblastoma	GDSC	GPAAPVTPT	DEG_SIAH_1	140:148	Mutation rewiring degron network	0.1111
p.R156P	SIDM00380	Acute Myeloid Leukemia	GDSC	GPAAPVTPT	DEG_SIAH_1	140:148	Mutation rewiring degron network	0.1111

Kaplan plot for RASSF7 in

Select cancer type:
Download patient class data (Lower:Upper = 50%:50%)

*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

RASSF7

UniProt ID: Q02833

Entrez ID: 8045

Protein name: Ras association domain-containing protein 7 (HRAS1-related cluster protein 1)

External links: UniprotKB HGNC RefSeq COSMIC

Data table is loading....

Kaplan plot for RASSF7 in