DegronMD - Q03591(CFHR1)

CFHR1

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.V92L	TCGA-17-Z045	LUAD	TCGA	FFPFVE	LIG_APCC_ABBA_1	88:93	Mutation altering degron motif	0.5654
p.G95C	TCGA-66-2770	LUSC	TCGA	FFPFVE	LIG_APCC_ABBA_1	88:93	Mutation rewiring degron network	0.2778
p.G95C	DO27556	LUSC	ICGC	FFPFVE	LIG_APCC_ABBA_1	88:93	Mutation rewiring degron network	0.2778
p.P90H	TCGA-AZ-4315	COAD	TCGA	FFPFVE	LIG_APCC_ABBA_1	88:93	Mutation altering degron motif	0.7694
p.P90H	DO8842	COAD	ICGC	FFPFVE	LIG_APCC_ABBA_1	88:93	Mutation altering degron motif	0.7694
p.G101V	DO229024	LICA	ICGC	FFPFVE	LIG_APCC_ABBA_1	88:93	Mutation rewiring degron network	0.1111
p.T80P	DO52682	MALY	ICGC	FFPFVE	LIG_APCC_ABBA_1	88:93	Mutation rewiring degron network	0.1111
p.H96R	SIDM01242	Melanoma	GDSC	FFPFVE	LIG_APCC_ABBA_1	88:93	Mutation rewiring degron network	0.25
p.H96R	ACH-002162	Skin Cancer	CCLE	FFPFVE	LIG_APCC_ABBA_1	88:93	Mutation rewiring degron network	0.25
p.H96R	MMAC-SF	skin	COSMIC	FFPFVE	LIG_APCC_ABBA_1	88:93	Mutation rewiring degron network	0.25
p.L86Q	SIDM00256	Neuroblastoma	GDSC	FFPFVE	LIG_APCC_ABBA_1	88:93	Mutation rewiring degron network	0.2778
p.L86Q	ACH-002281	Neuroblastoma	CCLE	FFPFVE	LIG_APCC_ABBA_1	88:93	Mutation rewiring degron network	0.2778
p.L86Q	NB14	autonomic ganglia	COSMIC	FFPFVE	LIG_APCC_ABBA_1	88:93	Mutation rewiring degron network	0.2778

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*NOTE: the Kaplan plots were collected from OncoLnc