DegronMD - Q03692(COL10A1)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.P538S	TCGA-AJ-A3BH	UCEC	TCGA	LSGTPLVS	DEG_SCF_FBW7_1	534:541	Mutation altering degron motif	0.6752
p.P538S	DO41638	UCEC	ICGC	LSGTPLVS	DEG_SCF_FBW7_1	534:541	Mutation altering degron motif	0.6752
p.G545R	DO230334	COCA	ICGC	LSGTPLVS	DEG_SCF_FBW7_1	534:541	Mutation rewiring degron network	0.2222
p.G545R	DO229010	COCA	ICGC	LSGTPLVS	DEG_SCF_FBW7_1	534:541	Mutation rewiring degron network	0.2222
p.G545R	DO229016	COCA	ICGC	LSGTPLVS	DEG_SCF_FBW7_1	534:541	Mutation rewiring degron network	0.2222
p.G545R	DO229003	COCA	ICGC	LSGTPLVS	DEG_SCF_FBW7_1	534:541	Mutation rewiring degron network	0.2222
p.G545R	DO229005	COCA	ICGC	LSGTPLVS	DEG_SCF_FBW7_1	534:541	Mutation rewiring degron network	0.2222
p.G545R	DO229473	LAML	ICGC	LSGTPLVS	DEG_SCF_FBW7_1	534:541	Mutation rewiring degron network	0.2222
p.G545R	DO229505	LAML	ICGC	LSGTPLVS	DEG_SCF_FBW7_1	534:541	Mutation rewiring degron network	0.2222
p.G545R	DO230659	LAML	ICGC	LSGTPLVS	DEG_SCF_FBW7_1	534:541	Mutation rewiring degron network	0.2222
p.G545R	DO231140	LAML	ICGC	LSGTPLVS	DEG_SCF_FBW7_1	534:541	Mutation rewiring degron network	0.2222
p.G545R	DO229047	LICA	ICGC	LSGTPLVS	DEG_SCF_FBW7_1	534:541	Mutation rewiring degron network	0.2222
p.G545R	DO230990	LUSC	ICGC	LSGTPLVS	DEG_SCF_FBW7_1	534:541	Mutation rewiring degron network	0.2222
p.F525S	DO227987	COCA	ICGC	LSGTPLVS	DEG_SCF_FBW7_1	534:541	Mutation rewiring degron network	0.0833
p.N543K	DO229034	LICA	ICGC	LSGTPLVS	DEG_SCF_FBW7_1	534:541	Mutation rewiring degron network	0.2778
p.P550L	DO229050	LICA	ICGC	LSGTPLVS	DEG_SCF_FBW7_1	534:541	Mutation rewiring degron network	0.0833
p.S533R	SIDM00313	Hodgkin's Lymphoma	GDSC	LSGTPLVS	DEG_SCF_FBW7_1	534:541	Mutation rewiring degron network	0.3056
p.S533R	ACH-000702	Lymphoma	CCLE	LSGTPLVS	DEG_SCF_FBW7_1	534:541	Mutation rewiring degron network	0.3056
p.S533R	L-1236	haematopoietic and lymphoid tissue	COSMIC	LSGTPLVS	DEG_SCF_FBW7_1	534:541	Mutation rewiring degron network	0.3056

Kaplan plot for COL10A1 in

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

COL10A1

UniProt ID: Q03692

Entrez ID: 1300

Protein name: Collagen alpha-1(X) chain

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for COL10A1 in