DegronMD - Q04900(CD164)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.G143R	TCGA-55-8620	LUAD	TCGA	PSTTS	DEG_SPOP_SBC_1	132:136	Mutation rewiring degron network	0.1389
p.V117M	TCGA-5P-A9JW	KIRP	TCGA	SVSTATPVPTA	DEG_COP1_1	110:120	Mutation altering degron motif	0.7208
p.V117M	DO223943	KIRP	ICGC	SVSTATPVPTA	DEG_COP1_1	110:120	Mutation altering degron motif	0.7208
p.T144I	TCGA-A5-A0G1	UCEC	TCGA	PSTTS	DEG_SPOP_SBC_1	132:136	Mutation rewiring degron network	0.1111
p.P130S	TCGA-AD-6895	COAD	TCGA	SVSTATPVPTA	DEG_COP1_1	110:120	Mutation rewiring degron network	0.0556
p.P130S	TCGA-AD-6895	COAD	TCGA	PSTTS	DEG_SPOP_SBC_1	132:136	Mutation rewiring degron network	0.2778
p.P130S	DO8938	COAD	ICGC	SVSTATPVPTA	DEG_COP1_1	110:120	Mutation rewiring degron network	0.0556
p.P130S	DO8938	COAD	ICGC	PSTTS	DEG_SPOP_SBC_1	132:136	Mutation rewiring degron network	0.2778
p.S133F	TCGA-CD-5800	STAD	TCGA	PSTTS	DEG_SPOP_SBC_1	132:136	Mutation altering degron motif	0.6871
p.S133F	DO38431	STAD	ICGC	PSTTS	DEG_SPOP_SBC_1	132:136	Mutation altering degron motif	0.6871
p.S133C	TCGA-G2-A2EK	BLCA	TCGA	PSTTS	DEG_SPOP_SBC_1	132:136	Mutation altering degron motif	0.643
p.S133C	DO546	BLCA	ICGC	PSTTS	DEG_SPOP_SBC_1	132:136	Mutation altering degron motif	0.643
p.P116T	TCGA-GN-A26D	SKCM	TCGA	SVSTATPVPTA	DEG_COP1_1	110:120	Mutation altering degron motif	0.5919
p.P116T	DO37480	SKCM	ICGC	SVSTATPVPTA	DEG_COP1_1	110:120	Mutation altering degron motif	0.5919
p.T105M	TCGA-XK-AAIW	PRAD	TCGA	SVSTATPVPTA	DEG_COP1_1	110:120	Mutation rewiring degron network	0.1944
p.T105M	DO51407	PRAD	ICGC	SVSTATPVPTA	DEG_COP1_1	110:120	Mutation rewiring degron network	0.1944
p.T112K	DO228976	LICA	ICGC	SVSTATPVPTA	DEG_COP1_1	110:120	Mutation altering degron motif	0.7306
p.T135N	DO228986	LICA	ICGC	PSTTS	DEG_SPOP_SBC_1	132:136	Mutation altering degron motif	0.7055
p.S122Y	DO229015	LICA	ICGC	SVSTATPVPTA	DEG_COP1_1	110:120	Mutation rewiring degron network	0.2778
p.S122Y	DO229015	LICA	ICGC	PSTTS	DEG_SPOP_SBC_1	132:136	Mutation rewiring degron network	0.0556
p.L140M	DO229037	LICA	ICGC	PSTTS	DEG_SPOP_SBC_1	132:136	Mutation rewiring degron network	0.2222
p.K125E	DO230950	LUSC	ICGC	SVSTATPVPTA	DEG_COP1_1	110:120	Mutation substituting flanking lysine	0.3056
p.K125E	DO230950	LUSC	ICGC	PSTTS	DEG_SPOP_SBC_1	132:136	Mutation substituting flanking lysine	0.25
p.K125E	DO224638	LUSC	ICGC	SVSTATPVPTA	DEG_COP1_1	110:120	Mutation substituting flanking lysine	0.3056
p.K125E	DO224638	LUSC	ICGC	PSTTS	DEG_SPOP_SBC_1	132:136	Mutation substituting flanking lysine	0.25
p.S110A	DO220881	MELA	ICGC	SVSTATPVPTA	DEG_COP1_1	110:120	Mutation altering degron motif	0.7588
p.S110V	DO220881	MELA	ICGC	SVSTATPVPTA	DEG_COP1_1	110:120	Mutation altering degron motif	0.758
p.R125L	DO37703	SKCM	ICGC	SVSTATPVPTA	DEG_COP1_1	110:120	Mutation substituting flanking lysine	0.3056
p.R125L	DO37703	SKCM	ICGC	PSTTS	DEG_SPOP_SBC_1	132:136	Mutation substituting flanking lysine	0.25
p.T112I	DO42472	UCEC	ICGC	SVSTATPVPTA	DEG_COP1_1	110:120	Mutation altering degron motif	0.7078
p.S110F	ACH-001275	Sarcoma	CCLE	SVSTATPVPTA	DEG_COP1_1	110:120	Mutation altering degron motif	0.7982
p.A145G	NCI-H460	lung	COSMIC	PSTTS	DEG_SPOP_SBC_1	132:136	Mutation rewiring degron network	0.0833
p.A130G	NCI-H460	lung	COSMIC	SVSTATPVPTA	DEG_COP1_1	110:120	Mutation rewiring degron network	0.0556
p.A130G	NCI-H460	lung	COSMIC	PSTTS	DEG_SPOP_SBC_1	132:136	Mutation rewiring degron network	0.2778

Kaplan plot for CD164 in

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

CD164

UniProt ID: Q04900

Entrez ID: 8763

Protein name: Sialomucin core protein 24 (MUC-24) (Endolyn) (Multi-glycosylated core protein 24) (MGC-24) (MGC-24v) (CD antigen CD164)

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for CD164 in