DegronMD - Q05682(CALD1)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.E78K	TCGA-AC-A23H	BRCA	TCGA	AKTTT	DEG_SPOP_SBC_1	79:83	Mutation rewiring degron network	0.3056
p.D92Y	TCGA-KL-8335	KICH	TCGA	AKTTT	DEG_SPOP_SBC_1	79:83	Mutation rewiring degron network	0.0833
p.E72K	DO2401	BRCA	ICGC	AKTTT	DEG_SPOP_SBC_1	79:83	Mutation rewiring degron network	0.1389
p.R93H	DO234401	ESAD	ICGC	AKTTT	DEG_SPOP_SBC_1	79:83	Mutation rewiring degron network	0.0556
p.R93H	DO229213	THCA	ICGC	AKTTT	DEG_SPOP_SBC_1	79:83	Mutation rewiring degron network	0.0556
p.D86Y	DO220343	KICH	ICGC	AKTTT	DEG_SPOP_SBC_1	79:83	Mutation blocking phosphorylation signal	0.6944
p.F90L	DO221125	MALY	ICGC	AKTTT	DEG_SPOP_SBC_1	79:83	Mutation rewiring degron network	0.1389
p.E92K	DO42201	UCEC	ICGC	AKTTT	DEG_SPOP_SBC_1	79:83	Mutation rewiring degron network	0.0833
p.R93C	DO42608	UCEC	ICGC	AKTTT	DEG_SPOP_SBC_1	79:83	Mutation rewiring degron network	0.0556

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons