DegronMD - Q06520(SULT2A1)

SULT2A1

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.M228I	TCGA-55-A490	LUAD	TCGA	MKENK	DEG_APCC_KENBOX_2	223:227	Mutation rewiring degron network	0.3056
p.M228I	DO24596	LUAD	ICGC	MKENK	DEG_APCC_KENBOX_2	223:227	Mutation rewiring degron network	0.3056
p.L215I	TCGA-EO-A22X	UCEC	TCGA	MKENK	DEG_APCC_KENBOX_2	223:227	Mutation rewiring degron network	0.1111
p.L215I	DO229028	LICA	ICGC	MKENK	DEG_APCC_KENBOX_2	223:227	Mutation rewiring degron network	0.1111
p.L215I	DO43907	UCEC	ICGC	MKENK	DEG_APCC_KENBOX_2	223:227	Mutation rewiring degron network	0.1111
p.N217S	TCGA-ND-A4WC	UCS	TCGA	MKENK	DEG_APCC_KENBOX_2	223:227	Mutation rewiring degron network	0.1667
p.K224E	TCGA-XF-AAN0	BLCA	TCGA	MKENK	DEG_APCC_KENBOX_2	223:227	Mutation altering degron motif	0.7022
p.K224E	DO51941	BLCA	ICGC	MKENK	DEG_APCC_KENBOX_2	223:227	Mutation altering degron motif	0.7022
p.V236A	DO6519	CLLE	ICGC	MKENK	DEG_APCC_KENBOX_2	223:227	Mutation rewiring degron network	0.0833
p.S232Y	DO50755	LICA	ICGC	MKENK	DEG_APCC_KENBOX_2	223:227	Mutation rewiring degron network	0.1944
p.N230I	SIDM00107	Melanoma	GDSC	MKENK	DEG_APCC_KENBOX_2	223:227	Mutation rewiring degron network	0.25
p.N230I	SIDM01520	Oral Cavity Carcinoma	GDSC	MKENK	DEG_APCC_KENBOX_2	223:227	Mutation rewiring degron network	0.25

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*NOTE: the Kaplan plots were collected from OncoLnc