DegronMD - Q07065(CKAP4)

CKAP4

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.E308K	TCGA-A5-A1OF	UCEC	TCGA	LRSTLQTME	DEG_APCC_DBOX_1	310:318	Mutation rewiring degron network	0.2778
p.E308K	DO42568	UCEC	ICGC	LRSTLQTME	DEG_APCC_DBOX_1	310:318	Mutation rewiring degron network	0.2778
p.E327K	TCGA-AG-A002	READ	TCGA	LRSTLQTME	DEG_APCC_DBOX_1	310:318	Mutation rewiring degron network	0.0833
p.E324D	TCGA-AP-A051	UCEC	TCGA	LRSTLQTME	DEG_APCC_DBOX_1	310:318	Mutation rewiring degron network	0.1667
p.E324D	DO42673	UCEC	ICGC	LRSTLQTME	DEG_APCC_DBOX_1	310:318	Mutation rewiring degron network	0.1667
p.R303G	TCGA-B0-5705	KIRC	TCGA	LRSTLQTME	DEG_APCC_DBOX_1	310:318	Mutation rewiring degron network	0.1389
p.R303G	DO19913	KIRC	ICGC	LRSTLQTME	DEG_APCC_DBOX_1	310:318	Mutation rewiring degron network	0.1389
p.R326C	TCGA-CG-4306	STAD	TCGA	LRSTLQTME	DEG_APCC_DBOX_1	310:318	Mutation rewiring degron network	0.1111
p.R326C	DO38567	STAD	ICGC	LRSTLQTME	DEG_APCC_DBOX_1	310:318	Mutation rewiring degron network	0.1111
p.S302F	TCGA-VQ-A8PT	STAD	TCGA	LRSTLQTME	DEG_APCC_DBOX_1	310:318	Mutation rewiring degron network	0.1111
p.S302F	DO51776	STAD	ICGC	LRSTLQTME	DEG_APCC_DBOX_1	310:318	Mutation rewiring degron network	0.1111
p.L314I	TCGA-XK-AAIW	PRAD	TCGA	LRSTLQTME	DEG_APCC_DBOX_1	310:318	Mutation altering degron motif	0.7174
p.L314I	DO51407	PRAD	ICGC	LRSTLQTME	DEG_APCC_DBOX_1	310:318	Mutation altering degron motif	0.7174
p.A309P	DO228299	LICA	ICGC	LRSTLQTME	DEG_APCC_DBOX_1	310:318	Mutation rewiring degron network	0.3056
p.A309S	DO50929	LICA	ICGC	LRSTLQTME	DEG_APCC_DBOX_1	310:318	Mutation rewiring degron network	0.3056

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*NOTE: the Kaplan plots were collected from OncoLnc