DegronMD - Q12829(RAB40B)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.S265I	TCGA-FI-A2D5	UCEC	TCGA	KRSSLRKVK	DEG_APCC_DBOX_1	250:258	Mutation rewiring degron network	0.1389
p.R261C	TCGA-HF-A5NB	STAD	TCGA	KRSSLRKVK	DEG_APCC_DBOX_1	250:258	Mutation rewiring degron network	0.25
p.R255H	DO233898	GACA	ICGC	KRSSLRKVK	DEG_APCC_DBOX_1	250:258	Mutation altering degron motif	0.7133
p.R261S	DO229221	THCA	ICGC	KRSSLRKVK	DEG_APCC_DBOX_1	250:258	Mutation rewiring degron network	0.25
p.K256N	SIDM00516	Melanoma	GDSC	KRSSLRKVK	DEG_APCC_DBOX_1	250:258	Mutation altering degron motif	0.5806
p.K256N	MZ7-mel	skin	COSMIC	KRSSLRKVK	DEG_APCC_DBOX_1	250:258	Mutation altering degron motif	0.5806

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons