DegronMD - Q13309(SKP2)

SKP2

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.P10T	TCGA-AN-A046	BRCA	TCGA	HRKHLQEIP	DEG_APCC_DBOX_1	2:10	Mutation altering degron motif	0.5919
p.P10T	DO1285	BRCA	ICGC	HRKHLQEIP	DEG_APCC_DBOX_1	2:10	Mutation altering degron motif	0.5919
p.K4R	TCGA-DD-A1EK	LIHC	TCGA	HRKHLQEIP	DEG_APCC_DBOX_1	2:10	Mutation altering degron motif	0.6126
p.K4R	DO48492	LIHC	ICGC	HRKHLQEIP	DEG_APCC_DBOX_1	2:10	Mutation altering degron motif	0.6126
p.L12Q	TCGA-DU-7007	LGG	TCGA	HRKHLQEIP	DEG_APCC_DBOX_1	2:10	Mutation rewiring degron network	0.2778
p.L12Q	DO22400	LGG	ICGC	HRKHLQEIP	DEG_APCC_DBOX_1	2:10	Mutation rewiring degron network	0.2778
p.S10G	DO7810	COAD	ICGC	HRKHLQEIP	DEG_APCC_DBOX_1	2:10	Mutation altering degron motif	0.6993
p.N15S	SIDM00537	Colorectal Carcinoma	GDSC	HRKHLQEIP	DEG_APCC_DBOX_1	2:10	Mutation rewiring degron network	0.1944
p.N15S	ACH-000982	Colon/Colorectal Cancer	CCLE	HRKHLQEIP	DEG_APCC_DBOX_1	2:10	Mutation rewiring degron network	0.1944
p.N15S	ACH-001345	Colon/Colorectal Cancer	CCLE	HRKHLQEIP	DEG_APCC_DBOX_1	2:10	Mutation rewiring degron network	0.1944
p.N15S	GP5d	large intestine	COSMIC	HRKHLQEIP	DEG_APCC_DBOX_1	2:10	Mutation rewiring degron network	0.1944
p.L5F	DMS-79	lung	COSMIC	HRKHLQEIP	DEG_APCC_DBOX_1	2:10	Mutation altering degron motif	0.6981
p.A13T	SNU-1040	large intestine	COSMIC	HRKHLQEIP	DEG_APCC_DBOX_1	2:10	Mutation rewiring degron network	0.25
p.A6S	DMS-79	lung	COSMIC	HRKHLQEIP	DEG_APCC_DBOX_1	2:10	Mutation altering degron motif	0.7588

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*NOTE: the Kaplan plots were collected from OncoLnc