DegronMD - Q13557(CAMK2D)

CAMK2D

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.I499T	TCGA-AX-A05Z	UCEC	TCGA	GKENF	DEG_APCC_KENBOX_2	485:489	Mutation rewiring degron network	0.0556
p.P480S	TCGA-ER-A193	SKCM	TCGA	GKENF	DEG_APCC_KENBOX_2	485:489	Mutation rewiring degron network	0.1944
p.W489C	DO10443	COAD	ICGC	GKENF	DEG_APCC_KENBOX_2	485:489	Mutation altering degron motif	0.7
p.R492Q	DO222741	COCA	ICGC	GKENF	DEG_APCC_KENBOX_2	485:489	Mutation rewiring degron network	0.25
p.H490Q	DO229034	LICA	ICGC	GKENF	DEG_APCC_KENBOX_2	485:489	Mutation blocking phosphorylation signal	0.75
p.D493N	DO27580	LUSC	ICGC	GKENF	DEG_APCC_KENBOX_2	485:489	Mutation rewiring degron network	0.2222
p.M477I	DO32347	OV	ICGC	GKENF	DEG_APCC_KENBOX_2	485:489	Mutation rewiring degron network	0.1111
p.R487C	DO223286	UCEC	ICGC	GKENF	DEG_APCC_KENBOX_2	485:489	Mutation altering degron motif	0.8301
p.G482W	SN12C	kidney	COSMIC	GKENF	DEG_APCC_KENBOX_2	485:489	Mutation rewiring degron network	0.25
p.G485W	SN12C	kidney	COSMIC	GKENF	DEG_APCC_KENBOX_2	485:489	Mutation altering degron motif	0.6714

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*NOTE: the Kaplan plots were collected from OncoLnc