DegronMD - Q13574(DGKZ)

DGKZ

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.V407M	TCGA-27-2523	GBM	TCGA	NWGGGYTDEP	CBL_PTK	391:400	Mutation rewiring degron network	0.1389
p.S405N	TCGA-GN-A269	SKCM	TCGA	NWGGGYTDEP	CBL_PTK	391:400	Mutation rewiring degron network	0.1944
p.S405N	SIDM01618	B-Lymphoblastic Leukemia	GDSC	NWGGGYTDEP	CBL_PTK	391:400	Mutation rewiring degron network	0.1944
p.S405N	ACH-000942	Leukemia	CCLE	NWGGGYTDEP	CBL_PTK	391:400	Mutation rewiring degron network	0.1944
p.F386L	TCGA-R6-A6Y0	ESCA	TCGA	NWGGGYTDEP	CBL_PTK	391:400	Mutation rewiring degron network	0.1944
p.E402D	DO222566	BTCA	ICGC	NWGGGYTDEP	CBL_PTK	391:400	Mutation rewiring degron network	0.2778
p.E402K	DO10582	COAD	ICGC	NWGGGYTDEP	CBL_PTK	391:400	Mutation rewiring degron network	0.2778
p.L394M	DO232858	NACA	ICGC	NWGGGYTDEP	CBL_PTK	391:400	Mutation altering degron motif	0.711
p.I391M	SIDM00266	Ewing's Sarcoma	GDSC	NWGGGYTDEP	CBL_PTK	391:400	Mutation altering degron motif	0.7618
p.I391M	ACH-002103	Bone Cancer	CCLE	NWGGGYTDEP	CBL_PTK	391:400	Mutation altering degron motif	0.7618
p.I391M	ES1	bone	COSMIC	NWGGGYTDEP	CBL_PTK	391:400	Mutation altering degron motif	0.7618

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*NOTE: the Kaplan plots were collected from OncoLnc