DegronMD - Q13724(MOGS)

MOGS

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.E744D	TCGA-13-1411	OV	TCGA	AASSS	DEG_SPOP_SBC_1	732:736	Mutation rewiring degron network	0.1111
p.E744V	TCGA-13-1411	OV	TCGA	AASSS	DEG_SPOP_SBC_1	732:736	Mutation rewiring degron network	0.1111
p.S730Y	TCGA-18-3409	LUSC	TCGA	AASSS	DEG_SPOP_SBC_1	732:736	Mutation rewiring degron network	0.2778
p.A646V	TCGA-62-A46P	LUAD	TCGA	LGVFAD	LIG_APCC_ABBA_1	649:654	Mutation rewiring degron network	0.25
p.E642Q	TCGA-63-A5MH	LUSC	TCGA	LGVFAD	LIG_APCC_ABBA_1	649:654	Mutation rewiring degron network	0.1389
p.R741H	TCGA-B5-A3FC	UCEC	TCGA	AASSS	DEG_SPOP_SBC_1	732:736	Mutation rewiring degron network	0.1944
p.G656V	TCGA-BF-A1Q0	SKCM	TCGA	LGVFAD	LIG_APCC_ABBA_1	649:654	Mutation rewiring degron network	0.2778
p.H644Y	TCGA-ND-A4WC	UCS	TCGA	LGVFAD	LIG_APCC_ABBA_1	649:654	Mutation rewiring degron network	0.1944
p.R645W	DO223732	CESC	ICGC	LGVFAD	LIG_APCC_ABBA_1	649:654	Mutation rewiring degron network	0.2222
p.R645W	DO233270	GACA	ICGC	LGVFAD	LIG_APCC_ABBA_1	649:654	Mutation rewiring degron network	0.2222
p.L722H	DO11100	GBM	ICGC	AASSS	DEG_SPOP_SBC_1	732:736	Mutation rewiring degron network	0.0556
p.A656T	DO47817	STAD	ICGC	LGVFAD	LIG_APCC_ABBA_1	649:654	Mutation rewiring degron network	0.2778
p.A647V	LNCaP-Clone-FGC	prostate	COSMIC	LGVFAD	LIG_APCC_ABBA_1	649:654	Mutation rewiring degron network	0.2778
p.L660R	NCI-SNU-1	stomach	COSMIC	LGVFAD	LIG_APCC_ABBA_1	649:654	Mutation substituting flanking lysine	0.2778

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*NOTE: the Kaplan plots were collected from OncoLnc