DegronMD - Q13884(SNTB1)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.R31L	TCGA-BF-A1Q0	SKCM	TCGA	QRSGLLEVL	DEG_APCC_DBOX_1	21:29	Mutation rewiring degron network	0.2778
p.R31L	TCGA-CQ-5326	HNSC	TCGA	QRSGLLEVL	DEG_APCC_DBOX_1	21:29	Mutation rewiring degron network	0.2778
p.R31L	TCGA-CX-7219	HNSC	TCGA	QRSGLLEVL	DEG_APCC_DBOX_1	21:29	Mutation rewiring degron network	0.2778
p.R31L	TCGA-D3-A2JG	SKCM	TCGA	QRSGLLEVL	DEG_APCC_DBOX_1	21:29	Mutation rewiring degron network	0.2778
p.R31L	TCGA-ER-A19H	SKCM	TCGA	QRSGLLEVL	DEG_APCC_DBOX_1	21:29	Mutation rewiring degron network	0.2778
p.R31L	DO14910	HNSC	ICGC	QRSGLLEVL	DEG_APCC_DBOX_1	21:29	Mutation rewiring degron network	0.2778
p.R31L	DO15286	HNSC	ICGC	QRSGLLEVL	DEG_APCC_DBOX_1	21:29	Mutation rewiring degron network	0.2778
p.R31L	DO47299	SKCM	ICGC	QRSGLLEVL	DEG_APCC_DBOX_1	21:29	Mutation rewiring degron network	0.2778
p.R31L	DO47374	SKCM	ICGC	QRSGLLEVL	DEG_APCC_DBOX_1	21:29	Mutation rewiring degron network	0.2778
p.R31L	DO47613	SKCM	ICGC	QRSGLLEVL	DEG_APCC_DBOX_1	21:29	Mutation rewiring degron network	0.2778
p.G24W	TCGA-D3-A1Q1	SKCM	TCGA	QRSGLLEVL	DEG_APCC_DBOX_1	21:29	Mutation altering degron motif	0.6714
p.G24W	TCGA-DA-A1I5	SKCM	TCGA	QRSGLLEVL	DEG_APCC_DBOX_1	21:29	Mutation altering degron motif	0.6714
p.G24W	DO37447	SKCM	ICGC	QRSGLLEVL	DEG_APCC_DBOX_1	21:29	Mutation altering degron motif	0.6714
p.G24W	DO37445	SKCM	ICGC	QRSGLLEVL	DEG_APCC_DBOX_1	21:29	Mutation altering degron motif	0.6714
p.V37G	TCGA-FF-8042	DLBC	TCGA	QRSGLLEVL	DEG_APCC_DBOX_1	21:29	Mutation rewiring degron network	0.1111
p.V37G	DO222306	DLBC	ICGC	QRSGLLEVL	DEG_APCC_DBOX_1	21:29	Mutation rewiring degron network	0.1111
p.D32Y	DO218553	BRCA	ICGC	QRSGLLEVL	DEG_APCC_DBOX_1	21:29	Mutation rewiring degron network	0.25
p.G24R	DO50332	ESAD	ICGC	QRSGLLEVL	DEG_APCC_DBOX_1	21:29	Mutation altering degron motif	0.6457
p.R19L	DO229259	THCA	ICGC	QRSGLLEVL	DEG_APCC_DBOX_1	21:29	Mutation rewiring degron network	0.2778
p.D32N	DO229544	UTCA	ICGC	QRSGLLEVL	DEG_APCC_DBOX_1	21:29	Mutation rewiring degron network	0.25
p.L25M	SIDM00915	Small Cell Lung Carcinoma	GDSC	QRSGLLEVL	DEG_APCC_DBOX_1	21:29	Mutation altering degron motif	0.711
p.R19Q	SIDM00600	Thyroid Gland Carcinoma	GDSC	QRSGLLEVL	DEG_APCC_DBOX_1	21:29	Mutation rewiring degron network	0.2778
p.R19Q	SIDM01144	Gastric Carcinoma	GDSC	QRSGLLEVL	DEG_APCC_DBOX_1	21:29	Mutation rewiring degron network	0.2778
p.R19Q	SIDM00592	Oral Cavity Carcinoma	GDSC	QRSGLLEVL	DEG_APCC_DBOX_1	21:29	Mutation rewiring degron network	0.2778
p.R19Q	SIDM00533	Pancreatic Carcinoma	GDSC	QRSGLLEVL	DEG_APCC_DBOX_1	21:29	Mutation rewiring degron network	0.2778
p.R19Q	SIDM00466	Ovarian Carcinoma	GDSC	QRSGLLEVL	DEG_APCC_DBOX_1	21:29	Mutation rewiring degron network	0.2778
p.R19Q	SIDM01093	Cervical Carcinoma	GDSC	QRSGLLEVL	DEG_APCC_DBOX_1	21:29	Mutation rewiring degron network	0.2778
p.R19Q	SIDM00556	Neuroblastoma	GDSC	QRSGLLEVL	DEG_APCC_DBOX_1	21:29	Mutation rewiring degron network	0.2778
p.R19Q	SIDM01029	Esophageal Squamous Cell Carcinoma	GDSC	QRSGLLEVL	DEG_APCC_DBOX_1	21:29	Mutation rewiring degron network	0.2778
p.R19Q	SIDM00077	Oral Cavity Carcinoma	GDSC	QRSGLLEVL	DEG_APCC_DBOX_1	21:29	Mutation rewiring degron network	0.2778
p.R19Q	SIDM00575	Glioma	GDSC	QRSGLLEVL	DEG_APCC_DBOX_1	21:29	Mutation rewiring degron network	0.2778

Kaplan plot for SNTB1 in

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

SNTB1

UniProt ID: Q13884

Entrez ID: 6641

Protein name: Beta-1-syntrophin (59 kDa dystrophin-associated protein A1 basic component 1) (DAPA1B) (BSYN2) (Syntrophin-2) (Tax interaction protein 43) (TIP-43)

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for SNTB1 in