DegronMD - Q13895(BYSL)

GO - Biological processes (BP): View more >>

GO - Molecular function (MF): View more >>

GO - Cellular component (CC): View more >>

Choose a PDB ID:
Open in full screen with detailed sequence annotations

Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.A143V	TCGA-D3-A3MR	SKCM	TCGA	ARRTLADII	DEG_APCC_DBOX_1	143:151	Mutation altering degron motif	0.5825
p.A143V	DO47256	SKCM	ICGC	ARRTLADII	DEG_APCC_DBOX_1	143:151	Mutation altering degron motif	0.5825
p.R145H	TCGA-EI-6917	READ	TCGA	ARRTLADII	DEG_APCC_DBOX_1	143:151	Mutation altering degron motif	0.7133
p.R145H	DO36881	READ	ICGC	ARRTLADII	DEG_APCC_DBOX_1	143:151	Mutation altering degron motif	0.7133
p.P142S	DO222702	MELA	ICGC	ARRTLADII	DEG_APCC_DBOX_1	143:151	Mutation rewiring degron network	0.3056

Select cancer type:
Download patient class data (Lower:Upper = 50%:50%)

*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons