DegronMD - Q14003(KCNC3)

KCNC3

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.R98H	TCGA-JW-A69B	CESC	TCGA	YRSTLRTLP	DEG_APCC_DBOX_1	102:110	Mutation rewiring degron network	0.2222
p.R98H	DO49977	CESC	ICGC	YRSTLRTLP	DEG_APCC_DBOX_1	102:110	Mutation rewiring degron network	0.2222
p.P120T	DO230326	COCA	ICGC	YRSTLRTLP	DEG_APCC_DBOX_1	102:110	Mutation rewiring degron network	0.0556
p.P114L	DO233732	GACA	ICGC	YRSTLRTLP	DEG_APCC_DBOX_1	102:110	Mutation rewiring degron network	0.2222
p.P115L	DO228435	MALY	ICGC	YRSTLRTLP	DEG_APCC_DBOX_1	102:110	Mutation rewiring degron network	0.1944
p.S117F	DO232555	PBCA	ICGC	YRSTLRTLP	DEG_APCC_DBOX_1	102:110	Mutation rewiring degron network	0.1389
p.R107G	DO229499	SKCA	ICGC	YRSTLRTLP	DEG_APCC_DBOX_1	102:110	Mutation altering degron motif	0.6457
p.T105M	DO229245	THCA	ICGC	YRSTLRTLP	DEG_APCC_DBOX_1	102:110	Mutation altering degron motif	0.6312
p.L114M	SIDM00403	T-Lymphoblastic Leukemia	GDSC	YRSTLRTLP	DEG_APCC_DBOX_1	102:110	Mutation rewiring degron network	0.2222
p.L114M	ACH-000636	Leukemia	CCLE	YRSTLRTLP	DEG_APCC_DBOX_1	102:110	Mutation rewiring degron network	0.2222
p.Y102C	SIDM01007	T-Lymphoblastic Leukemia	GDSC	YRSTLRTLP	DEG_APCC_DBOX_1	102:110	Mutation altering degron motif	0.7087
p.V97M	SIDM00946	T-Lymphoblastic Leukemia	GDSC	YRSTLRTLP	DEG_APCC_DBOX_1	102:110	Mutation rewiring degron network	0.1944

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*NOTE: the Kaplan plots were collected from OncoLnc