DegronMD - Q14139(UBE4A)

UBE4A

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.H86Y	TCGA-21-1082	LUSC	TCGA	QRIFLITLD	DEG_APCC_DBOX_1	89:97	Mutation rewiring degron network	0.25
p.H86Y	DO26463	LUSC	ICGC	QRIFLITLD	DEG_APCC_DBOX_1	89:97	Mutation rewiring degron network	0.25
p.P101H	TCGA-EE-A2GT	SKCM	TCGA	QRIFLITLD	DEG_APCC_DBOX_1	89:97	Mutation rewiring degron network	0.2222
p.P101H	DO36556	READ	ICGC	QRIFLITLD	DEG_APCC_DBOX_1	89:97	Mutation rewiring degron network	0.2222
p.P101H	DO37946	SKCM	ICGC	QRIFLITLD	DEG_APCC_DBOX_1	89:97	Mutation rewiring degron network	0.2222
p.I91F	DO223442	CLLE	ICGC	QRIFLITLD	DEG_APCC_DBOX_1	89:97	Mutation altering degron motif	0.6304
p.C79F	DO229027	LICA	ICGC	QRIFLITLD	DEG_APCC_DBOX_1	89:97	Mutation rewiring degron network	0.0556
p.E80D	DO229037	LICA	ICGC	QRIFLITLD	DEG_APCC_DBOX_1	89:97	Mutation rewiring degron network	0.0833
p.D106N	HCT-15	large intestine	COSMIC	QRIFLITLD	DEG_APCC_DBOX_1	89:97	Mutation rewiring degron network	0.0833

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*NOTE: the Kaplan plots were collected from OncoLnc