DegronMD - Q14534(SQLE)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.V126L	TCGA-ZF-AA58	BLCA	TCGA	ACTST	DEG_SPOP_SBC_1	114:118	Mutation rewiring degron network	0.1111
p.V126L	DO219100	BLCA	ICGC	ACTST	DEG_SPOP_SBC_1	114:118	Mutation rewiring degron network	0.1111
p.Q124H	DO229034	LICA	ICGC	ACTST	DEG_SPOP_SBC_1	114:118	Mutation rewiring degron network	0.1667
p.P124L	DO27915	ORCA	ICGC	ACTST	DEG_SPOP_SBC_1	114:118	Mutation rewiring degron network	0.1667
p.P114S	DO37422	SKCM	ICGC	ACTST	DEG_SPOP_SBC_1	114:118	Mutation altering degron motif	0.6752
p.T112I	SIDM01118	Small Cell Lung Carcinoma	GDSC	ACTST	DEG_SPOP_SBC_1	114:118	Mutation rewiring degron network	0.2778
p.T112I	ACH-002175	Lung Cancer	CCLE	ACTST	DEG_SPOP_SBC_1	114:118	Mutation rewiring degron network	0.2778
p.T112I	NCI-H740	lung	COSMIC	ACTST	DEG_SPOP_SBC_1	114:118	Mutation rewiring degron network	0.2778
p.L109V	ACH-002680	Brain Cancer	CCLE	ACTST	DEG_SPOP_SBC_1	114:118	Mutation rewiring degron network	0.1944

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons