FUNCTION: Caspase-like protease, which plays a central role in the chromosome segregation by cleaving the SCC1/RAD21 subunit of the cohesin complex at the onset of anaphase. During most of the cell cycle, it is inactivated by different mechanisms. {ECO:0000269|PubMed:10411507, ECO:0000269|PubMed:115...
FUNCTION: Caspase-like protease, which plays a central role in the chromosome segregation by cleaving the SCC1/RAD21 subunit of the cohesin complex at the onset of anaphase. During most of the cell cycle, it is inactivated by different mechanisms. {ECO:0000269|PubMed:10411507, ECO:0000269|PubMed:11509732}.
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GO - Biological processes (BP):
apoptotic process [GO:0006915]; establishment of mitotic spindle localization [GO:0040001]; homologous chromosome segregation [GO:0045143]; meiotic chromosome separation [GO:0051307]; meiotic spindle organization [GO:0000212]; mitotic cytokinesis [GO:0000281]; mitotic sister chromatid segregation [G...
apoptotic process [GO:0006915]; establishment of mitotic spindle localization [GO:0040001]; homologous chromosome segregation [GO:0045143]; meiotic chromosome separation [GO:0051307]; meiotic spindle organization [GO:0000212]; mitotic cytokinesis [GO:0000281]; mitotic sister chromatid segregation [GO:0000070]; negative regulation of sister chromatid cohesion [GO:0045875]; positive regulation of mitotic metaphase/anaphase transition [GO:0045842]
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GO - Molecular function (MF):
catalytic activity [GO:0003824]; cysteine-type endopeptidase activity [GO:0004197]; cysteine-type peptidase activity [GO:0008234]...
catalytic activity [GO:0003824]; cysteine-type endopeptidase activity [GO:0004197]; cysteine-type peptidase activity [GO:0008234]
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GO - Cellular component (CC):
centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitotic spindle [GO:0072686]; nucleus [GO:0005634]...
centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitotic spindle [GO:0072686]; nucleus [GO:0005634]
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