DegronMD - Q14703(MBTPS1)

MBTPS1

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.R619Q	TCGA-AG-A002	READ	TCGA	IIPTPPRS	DEG_SCF_FBW7_1	613:620	Mutation altering degron motif	0.6218
p.K621R	TCGA-NK-A5CR	LUSC	TCGA	IIPTPPRS	DEG_SCF_FBW7_1	613:620	Mutation rewiring degron network	0.3056
p.K621R	DO219207	LUSC	ICGC	IIPTPPRS	DEG_SCF_FBW7_1	613:620	Mutation rewiring degron network	0.3056
p.P618L	TCGA-XF-AAMH	BLCA	TCGA	IIPTPPRS	DEG_SCF_FBW7_1	613:620	Mutation altering degron motif	0.6471
p.P618L	DO51931	BLCA	ICGC	IIPTPPRS	DEG_SCF_FBW7_1	613:620	Mutation altering degron motif	0.6471
p.P618Q	DO228971	LICA	ICGC	IIPTPPRS	DEG_SCF_FBW7_1	613:620	Mutation altering degron motif	0.5924
p.P618S	DO220906	MELA	ICGC	IIPTPPRS	DEG_SCF_FBW7_1	613:620	Mutation altering degron motif	0.5641
p.P615S	DO229494	SKCA	ICGC	IIPTPPRS	DEG_SCF_FBW7_1	613:620	Mutation altering degron motif	0.5641
p.D626Y	DO229259	THCA	ICGC	IIPTPPRS	DEG_SCF_FBW7_1	613:620	Mutation rewiring degron network	0.1667

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*NOTE: the Kaplan plots were collected from OncoLnc