DegronMD - Q14865(ARID5B)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.H397R	TCGA-2Z-A9JG	KIRP	TCGA	PGSTS	DEG_SPOP_SBC_1	385:389	Mutation rewiring degron network	0.1111
p.R395H	TCGA-B5-A3FC	UCEC	TCGA	PGSTS	DEG_SPOP_SBC_1	385:389	Mutation rewiring degron network	0.1667
p.R395H	TCGA-CM-6162	COAD	TCGA	PGSTS	DEG_SPOP_SBC_1	385:389	Mutation rewiring degron network	0.1667
p.Y398C	TCGA-BT-A20O	BLCA	TCGA	PGSTS	DEG_SPOP_SBC_1	385:389	Mutation rewiring degron network	0.0833
p.G382D	TCGA-CR-7377	HNSC	TCGA	PGSTS	DEG_SPOP_SBC_1	385:389	Mutation rewiring degron network	0.25
p.S934G	TCGA-EI-6882	READ	TCGA	AHSTT	DEG_SPOP_SBC_1	925:929	Mutation rewiring degron network	0.1944
p.S387G	TCGA-P3-A6T0	HNSC	TCGA	PGSTS	DEG_SPOP_SBC_1	385:389	Mutation altering degron motif	0.6993
p.S933C	DO1132	BRCA	ICGC	AHSTT	DEG_SPOP_SBC_1	925:929	Mutation rewiring degron network	0.2222
p.A398T	DO9114	COAD	ICGC	PGSTS	DEG_SPOP_SBC_1	385:389	Mutation rewiring degron network	0.0833
p.A398V	DO233882	GACA	ICGC	PGSTS	DEG_SPOP_SBC_1	385:389	Mutation rewiring degron network	0.0833
p.A930S	DO229029	LICA	ICGC	AHSTT	DEG_SPOP_SBC_1	925:929	Mutation rewiring degron network	0.3056
p.Q928E	DO52212	LIHC	ICGC	AHSTT	DEG_SPOP_SBC_1	925:929	Mutation altering degron motif	0.6744
p.F931C	DO222638	MELA	ICGC	AHSTT	DEG_SPOP_SBC_1	925:929	Mutation rewiring degron network	0.2778
p.P932L	DO37422	SKCM	ICGC	AHSTT	DEG_SPOP_SBC_1	925:929	Mutation rewiring degron network	0.25
p.P921S	DO48726	SKCM	ICGC	AHSTT	DEG_SPOP_SBC_1	925:929	Mutation rewiring degron network	0.2222
p.Y379D	DO42129	UCEC	ICGC	PGSTS	DEG_SPOP_SBC_1	385:389	Mutation rewiring degron network	0.1667
p.K386N	DO41380	UCEC	ICGC	PGSTS	DEG_SPOP_SBC_1	385:389	Mutation altering degron motif	0.6918
p.S938F	SIDM00221	Melanoma	GDSC	AHSTT	DEG_SPOP_SBC_1	925:929	Mutation rewiring degron network	0.0833
p.S938F	ACH-002388	Skin Cancer	CCLE	AHSTT	DEG_SPOP_SBC_1	925:929	Mutation rewiring degron network	0.0833
p.V921F	ACH-001197	Lymphoma	CCLE	AHSTT	DEG_SPOP_SBC_1	925:929	Mutation rewiring degron network	0.2222
p.G383V	ACH-002256	Leukemia	CCLE	PGSTS	DEG_SPOP_SBC_1	385:389	Mutation rewiring degron network	0.2778
p.G383V	KARPAS-45	haematopoietic and lymphoid tissue	COSMIC	PGSTS	DEG_SPOP_SBC_1	385:389	Mutation rewiring degron network	0.2778
p.S933F	CP66-MEL	skin	COSMIC	AHSTT	DEG_SPOP_SBC_1	925:929	Mutation rewiring degron network	0.2222
p.D393E	TALL-1	haematopoietic and lymphoid tissue	COSMIC	PGSTS	DEG_SPOP_SBC_1	385:389	Mutation rewiring degron network	0.2222

Kaplan plot for ARID5B in

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

ARID5B

UniProt ID: Q14865

Entrez ID: 84159

Protein name: AT-rich interactive domain-containing protein 5B (ARID domain-containing protein 5B) (MRF1-like protein) (Modulator recognition factor 2) (MRF-2)

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for ARID5B in