DegronMD - Q14CZ8(HEPACAM)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.A345T	TCGA-4R-AA8I	LIHC	TCGA	PPGY	ITCH	337:340	Mutation rewiring degron network	0.1944
p.A345T	DO49657	LIHC	ICGC	PPGY	ITCH	337:340	Mutation rewiring degron network	0.1944
p.E162K	TCGA-A5-A0G2	UCEC	TCGA	VASTT	DEG_SPOP_SBC_1	152:156	Mutation rewiring degron network	0.1667
p.E162K	DO41235	UCEC	ICGC	VASTT	DEG_SPOP_SBC_1	152:156	Mutation rewiring degron network	0.1667
p.S146L	TCGA-AA-A010	COAD	TCGA	VASTT	DEG_SPOP_SBC_1	152:156	Mutation rewiring degron network	0.1667
p.S146L	TCGA-AZ-4315	COAD	TCGA	VASTT	DEG_SPOP_SBC_1	152:156	Mutation rewiring degron network	0.1667
p.S146L	TCGA-BR-8680	STAD	TCGA	VASTT	DEG_SPOP_SBC_1	152:156	Mutation rewiring degron network	0.1667
p.S146L	DO8842	COAD	ICGC	VASTT	DEG_SPOP_SBC_1	152:156	Mutation rewiring degron network	0.1667
p.S146L	DO47769	STAD	ICGC	VASTT	DEG_SPOP_SBC_1	152:156	Mutation rewiring degron network	0.1667
p.Q149R	TCGA-AD-5900	COAD	TCGA	VASTT	DEG_SPOP_SBC_1	152:156	Mutation rewiring degron network	0.25
p.Q149R	DO8514	COAD	ICGC	VASTT	DEG_SPOP_SBC_1	152:156	Mutation rewiring degron network	0.25
p.S161R	TCGA-HU-A4GH	STAD	TCGA	VASTT	DEG_SPOP_SBC_1	152:156	Mutation rewiring degron network	0.1944
p.S161R	DO47743	STAD	ICGC	VASTT	DEG_SPOP_SBC_1	152:156	Mutation rewiring degron network	0.1944
p.P335H	DO217836	ORCA	ICGC	PPGY	ITCH	337:340	Mutation rewiring degron network	0.2778
p.R330Q	SIDM01943	Colorectal Carcinoma	GDSC	PPGY	ITCH	337:340	Mutation rewiring degron network	0.1389

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons