DegronMD - Q15011(HERPUD1)

HERPUD1

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.S136Y	TCGA-12-0778	GBM	TCGA	QREVLRNLS	DEG_APCC_DBOX_1	127:135	Mutation rewiring degron network	0.3056
p.E118D	TCGA-B9-4117	KIRP	TCGA	QREVLRNLS	DEG_APCC_DBOX_1	127:135	Mutation rewiring degron network	0.0833
p.R132W	TCGA-EI-6917	READ	TCGA	QREVLRNLS	DEG_APCC_DBOX_1	127:135	Mutation altering degron motif	0.7523
p.S120F	TCGA-W3-AA1O	SKCM	TCGA	QREVLRNLS	DEG_APCC_DBOX_1	127:135	Mutation rewiring degron network	0.1389
p.E121Q	DO48399	BLCA	ICGC	QREVLRNLS	DEG_APCC_DBOX_1	127:135	Mutation rewiring degron network	0.1667
p.Y140C	DO219030	BLCA	ICGC	QREVLRNLS	DEG_APCC_DBOX_1	127:135	Mutation rewiring degron network	0.1944
p.G141W	DO228900	LICA	ICGC	QREVLRNLS	DEG_APCC_DBOX_1	127:135	Mutation rewiring degron network	0.1667
p.P132L	DO220891	MELA	ICGC	QREVLRNLS	DEG_APCC_DBOX_1	127:135	Mutation altering degron motif	0.7582
p.G136S	DO218960	PAAD	ICGC	QREVLRNLS	DEG_APCC_DBOX_1	127:135	Mutation rewiring degron network	0.3056
p.P137L	SIDM01617	Endometrial Carcinoma	GDSC	QREVLRNLS	DEG_APCC_DBOX_1	127:135	Mutation rewiring degron network	0.2778
p.P137L	ACH-000994	Endometrial/Uterine Cancer	CCLE	QREVLRNLS	DEG_APCC_DBOX_1	127:135	Mutation rewiring degron network	0.2778
p.H145R	IGROV-1	ovary	COSMIC	QREVLRNLS	DEG_APCC_DBOX_1	127:135	Mutation rewiring degron network	0.0556
p.S135Y	ESO51	oesophagus	COSMIC	QREVLRNLS	DEG_APCC_DBOX_1	127:135	Mutation altering degron motif	0.712

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*NOTE: the Kaplan plots were collected from OncoLnc