DegronMD - Q15366(PCBP2)

PCBP2

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.S290Y	TCGA-BS-A0UF	UCEC	TCGA	AQTTS	DEG_SPOP_SBC_1	285:289	Mutation rewiring degron network	0.3056
p.S296Y	DO52596	BOCA	ICGC	AQTTS	DEG_SPOP_SBC_1	285:289	Mutation rewiring degron network	0.1389
p.S294L	DO222363	MELA	ICGC	AQTTS	DEG_SPOP_SBC_1	285:289	Mutation rewiring degron network	0.1944
p.S294L	DO37635	SKCM	ICGC	AQTTS	DEG_SPOP_SBC_1	285:289	Mutation rewiring degron network	0.1944
p.S294L	DO47631	SKCM	ICGC	AQTTS	DEG_SPOP_SBC_1	285:289	Mutation rewiring degron network	0.1944
p.A275V	DO51545	PACA	ICGC	AQTTS	DEG_SPOP_SBC_1	285:289	Mutation rewiring degron network	0.0556
p.A280V	DO229229	THCA	ICGC	AQTTS	DEG_SPOP_SBC_1	285:289	Mutation rewiring degron network	0.1944
p.V291F	DO41253	UCEC	ICGC	AQTTS	DEG_SPOP_SBC_1	285:289	Mutation rewiring degron network	0.2778
p.S296T	DO42472	UCEC	ICGC	AQTTS	DEG_SPOP_SBC_1	285:289	Mutation rewiring degron network	0.1389
p.L282V	SIDM00118	Colorectal Carcinoma	GDSC	AQTTS	DEG_SPOP_SBC_1	285:289	Mutation rewiring degron network	0.25
p.L282V	HCC2998	large intestine	COSMIC	AQTTS	DEG_SPOP_SBC_1	285:289	Mutation rewiring degron network	0.25
p.L278V	ACH-001081	Colon/Colorectal Cancer	CCLE	AQTTS	DEG_SPOP_SBC_1	285:289	Mutation blocking phosphorylation signal	0.5833
p.L278V	HCC2998	large intestine	COSMIC	AQTTS	DEG_SPOP_SBC_1	285:289	Mutation blocking phosphorylation signal	0.5833
p.L281V	HCC2998	large intestine	COSMIC	AQTTS	DEG_SPOP_SBC_1	285:289	Mutation rewiring degron network	0.2222
p.L277V	HCC2998	large intestine	COSMIC	AQTTS	DEG_SPOP_SBC_1	285:289	Mutation rewiring degron network	0.1111

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*NOTE: the Kaplan plots were collected from OncoLnc