DegronMD - Q15459(SF3A1)

SF3A1

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.A635V	TCGA-AA-3663	COAD	TCGA	PPMIV	DEG_Kelch_actinfilin_1	644:648	Mutation rewiring degron network	0.0833
p.A635V	DO9346	COAD	ICGC	PPMIV	DEG_Kelch_actinfilin_1	644:648	Mutation rewiring degron network	0.0833
p.P636T	TCGA-EB-A24C	SKCM	TCGA	PPMIV	DEG_Kelch_actinfilin_1	644:648	Mutation rewiring degron network	0.1111
p.P636T	DO37438	SKCM	ICGC	PPMIV	DEG_Kelch_actinfilin_1	644:648	Mutation rewiring degron network	0.1111
p.P657L	TCGA-W3-AA21	SKCM	TCGA	PPMIV	DEG_Kelch_actinfilin_1	644:648	Mutation rewiring degron network	0.0833
p.P657L	DO51278	SKCM	ICGC	PPMIV	DEG_Kelch_actinfilin_1	644:648	Mutation rewiring degron network	0.0833
p.P644T	DO229022	LICA	ICGC	PPMIV	DEG_Kelch_actinfilin_1	644:648	Mutation altering degron motif	0.7031
p.R642P	DO229163	THCA	ICGC	PPMIV	DEG_Kelch_actinfilin_1	644:648	Mutation rewiring degron network	0.2778
p.M646L	DO229167	THCA	ICGC	PPMIV	DEG_Kelch_actinfilin_1	644:648	Mutation altering degron motif	0.711
p.P649T	ACH-002059	Leukemia	CCLE	PPMIV	DEG_Kelch_actinfilin_1	644:648	Mutation rewiring degron network	0.3056

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*NOTE: the Kaplan plots were collected from OncoLnc