DegronMD - Q15562(TEAD2)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.L193P	TCGA-DF-A2KN	UCEC	TCGA	LSLTPPST	DEG_SCF_FBW7_1	187:194	Mutation altering degron motif	0.7582
p.L193P	DO223282	UCEC	ICGC	LSLTPPST	DEG_SCF_FBW7_1	187:194	Mutation altering degron motif	0.7582
p.P196Q	TCGA-ER-A19C	SKCM	TCGA	LSLTPPST	DEG_SCF_FBW7_1	187:194	Mutation rewiring degron network	0.2778
p.P196Q	TCGA-FS-A1ZK	SKCM	TCGA	LSLTPPST	DEG_SCF_FBW7_1	187:194	Mutation rewiring degron network	0.2778
p.P196Q	DO37474	SKCM	ICGC	LSLTPPST	DEG_SCF_FBW7_1	187:194	Mutation rewiring degron network	0.2778
p.P196Q	DO47353	SKCM	ICGC	LSLTPPST	DEG_SCF_FBW7_1	187:194	Mutation rewiring degron network	0.2778
p.L200I	TCGA-FP-7829	STAD	TCGA	LSLTPPST	DEG_SCF_FBW7_1	187:194	Mutation rewiring degron network	0.1667
p.L200I	DO38308	STAD	ICGC	LSLTPPST	DEG_SCF_FBW7_1	187:194	Mutation rewiring degron network	0.1667
p.Y203H	DO222874	COCA	ICGC	LSLTPPST	DEG_SCF_FBW7_1	187:194	Mutation rewiring degron network	0.0833
p.Q186K	DO228976	LICA	ICGC	LSLTPPST	DEG_SCF_FBW7_1	187:194	Mutation rewiring degron network	0.3056
p.P183T	DO229211	THCA	ICGC	LSLTPPST	DEG_SCF_FBW7_1	187:194	Mutation rewiring degron network	0.2222
p.G184V	NCI-H1623	lung	COSMIC	LSLTPPST	DEG_SCF_FBW7_1	187:194	Mutation rewiring degron network	0.25

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons