DegronMD - Q15696(ZRSR2)

ZRSR2

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.Q32H	TCGA-CC-A8HT	LIHC	TCGA	RRQELARLR	DEG_APCC_DBOX_1	30:38	Mutation altering degron motif	0.647
p.Q32H	DO52187	LIHC	ICGC	RRQELARLR	DEG_APCC_DBOX_1	30:38	Mutation altering degron motif	0.647
p.E25D	TCGA-E6-A1M0	UCEC	TCGA	RRQELARLR	DEG_APCC_DBOX_1	30:38	Mutation rewiring degron network	0.1944
p.E25D	DO43682	UCEC	ICGC	RRQELARLR	DEG_APCC_DBOX_1	30:38	Mutation rewiring degron network	0.1944
p.E48K	TCGA-IR-A3LI	CESC	TCGA	RRQELARLR	DEG_APCC_DBOX_1	30:38	Mutation rewiring degron network	0.0556
p.E48K	DO44400	CESC	ICGC	RRQELARLR	DEG_APCC_DBOX_1	30:38	Mutation rewiring degron network	0.0556
p.R27Q	DO48368	BLCA	ICGC	RRQELARLR	DEG_APCC_DBOX_1	30:38	Mutation rewiring degron network	0.25
p.A35S	DO228948	LICA	ICGC	RRQELARLR	DEG_APCC_DBOX_1	30:38	Mutation altering degron motif	0.6477
p.A35S	DO229042	LICA	ICGC	RRQELARLR	DEG_APCC_DBOX_1	30:38	Mutation altering degron motif	0.6477
p.L34F	SIDM00683	Prostate Carcinoma	GDSC	RRQELARLR	DEG_APCC_DBOX_1	30:38	Mutation altering degron motif	0.6981
p.L34F	ACH-000977	lymph node	CCLE	RRQELARLR	DEG_APCC_DBOX_1	30:38	Mutation altering degron motif	0.6981
p.L34F	LNCaP-Clone-FGC	prostate	COSMIC	RRQELARLR	DEG_APCC_DBOX_1	30:38	Mutation altering degron motif	0.6981

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*NOTE: the Kaplan plots were collected from OncoLnc