DegronMD - Q15723(ELF2)

ELF2

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.V274A	TCGA-AA-3672	COAD	TCGA	QRGILAKVE	DEG_APCC_DBOX_1	273:281	Mutation altering degron motif	0.6936
p.L265I	TCGA-AP-A1E0	UCEC	TCGA	QRGILAKVE	DEG_APCC_DBOX_1	273:281	Mutation rewiring degron network	0.1111
p.L265I	TCGA-F5-6814	READ	TCGA	QRGILAKVE	DEG_APCC_DBOX_1	273:281	Mutation rewiring degron network	0.1111
p.L273I	TCGA-DX-A6YV	SARC	TCGA	QRGILAKVE	DEG_APCC_DBOX_1	273:281	Mutation altering degron motif	0.7174
p.P281L	TCGA-EO-A22R	UCEC	TCGA	QRGILAKVE	DEG_APCC_DBOX_1	273:281	Mutation altering degron motif	0.7582
p.S276F	DO50403	ESAD	ICGC	QRGILAKVE	DEG_APCC_DBOX_1	273:281	Mutation altering degron motif	0.7982
p.A291E	DO229019	LICA	ICGC	QRGILAKVE	DEG_APCC_DBOX_1	273:281	Mutation rewiring degron network	0.0556
p.V277F	DO25995	LUAD	ICGC	QRGILAKVE	DEG_APCC_DBOX_1	273:281	Mutation altering degron motif	0.7068
p.N282H	DO50291	SKCM	ICGC	QRGILAKVE	DEG_APCC_DBOX_1	273:281	Mutation rewiring degron network	0.3056
p.N282H	DO219773	UCEC	ICGC	QRGILAKVE	DEG_APCC_DBOX_1	273:281	Mutation rewiring degron network	0.3056

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*NOTE: the Kaplan plots were collected from OncoLnc