DegronMD - Q15916(ZBTB6)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.G229C	TCGA-AA-3966	COAD	TCGA	PCTSS	DEG_SPOP_SBC_1	238:242	Mutation rewiring degron network	0.0833
p.G229C	DO10068	COAD	ICGC	PCTSS	DEG_SPOP_SBC_1	238:242	Mutation rewiring degron network	0.0833
p.S236L	TCGA-C5-A7UH	CESC	TCGA	PCTSS	DEG_SPOP_SBC_1	238:242	Mutation rewiring degron network	0.2778
p.S236L	DO49891	CESC	ICGC	PCTSS	DEG_SPOP_SBC_1	238:242	Mutation rewiring degron network	0.2778
p.Q237L	DO222363	MELA	ICGC	PCTSS	DEG_SPOP_SBC_1	238:242	Mutation rewiring degron network	0.3056
p.S249C	DO232445	PBCA	ICGC	PCTSS	DEG_SPOP_SBC_1	238:242	Mutation rewiring degron network	0.1389
p.M246I	SIDM00460	B-Cell Non-Hodgkin's Lymphoma	GDSC	PCTSS	DEG_SPOP_SBC_1	238:242	Mutation rewiring degron network	0.2222
p.M246I	SIDM00717	Non-Cancerous	GDSC	PCTSS	DEG_SPOP_SBC_1	238:242	Mutation rewiring degron network	0.2222
p.M246I	SIDM00620	Glioblastoma	GDSC	PCTSS	DEG_SPOP_SBC_1	238:242	Mutation rewiring degron network	0.2222
p.M246I	SIDM01251	T-Cell Non-Hodgkin's Lymphoma	GDSC	PCTSS	DEG_SPOP_SBC_1	238:242	Mutation rewiring degron network	0.2222
p.M246I	SIDM00832	Colorectal Carcinoma	GDSC	PCTSS	DEG_SPOP_SBC_1	238:242	Mutation rewiring degron network	0.2222
p.M246I	SIDM01149	Small Cell Lung Carcinoma	GDSC	PCTSS	DEG_SPOP_SBC_1	238:242	Mutation rewiring degron network	0.2222
p.M246I	SIDM00835	Colorectal Carcinoma	GDSC	PCTSS	DEG_SPOP_SBC_1	238:242	Mutation rewiring degron network	0.2222
p.M246I	SIDM00733	Small Cell Lung Carcinoma	GDSC	PCTSS	DEG_SPOP_SBC_1	238:242	Mutation rewiring degron network	0.2222
p.M246I	SIDM00522	Small Cell Lung Carcinoma	GDSC	PCTSS	DEG_SPOP_SBC_1	238:242	Mutation rewiring degron network	0.2222
p.M246I	SIDM00103	Mesothelioma	GDSC	PCTSS	DEG_SPOP_SBC_1	238:242	Mutation rewiring degron network	0.2222
p.M246I	SIDM01101	Neuroblastoma	GDSC	PCTSS	DEG_SPOP_SBC_1	238:242	Mutation rewiring degron network	0.2222
p.M246I	SIDM00079	Ovarian Carcinoma	GDSC	PCTSS	DEG_SPOP_SBC_1	238:242	Mutation rewiring degron network	0.2222
p.M246I	SIDM01560	Rhabdomyosarcoma	GDSC	PCTSS	DEG_SPOP_SBC_1	238:242	Mutation rewiring degron network	0.2222
p.F248L	SIDM01611	Endometrial Carcinoma	GDSC	PCTSS	DEG_SPOP_SBC_1	238:242	Mutation rewiring degron network	0.1667
p.F248L	ACH-000996	Endometrial/Uterine Cancer	CCLE	PCTSS	DEG_SPOP_SBC_1	238:242	Mutation rewiring degron network	0.1667

Kaplan plot for ZBTB6 in

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

ZBTB6

UniProt ID: Q15916

Entrez ID: 10773

Protein name: Zinc finger and BTB domain-containing protein 6 (Zinc finger protein 482) (Zinc finger protein with interaction domain)

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for ZBTB6 in